ANXA9 and NDUFA4L2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ANXA9	NDUFA4L2
Gene Name		annexin A9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cell Surface Extracellular Vesicular Exosome
	Molecular Function	Phosphatidylserine Binding Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Acetylcholine Receptor Activity Protein Homodimerization Activity
	Biological Process	Synaptic Transmission Single Organismal Cell-cell Adhesion
Pathways
Drugs			NADH
Diseases
GWAS		Chronic kidney disease ( 20383146) Melanoma ( 21926416 21983785) Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		3 interactors: APP ARHGEF10L NDUFA4L2	13 interactors: ANXA9 C14orf1 C6orf62 COMMD8 DYNLL1 EIF3C KAT5 KCNA4 LUC7L2 PARK2 QTRT1 SLC35F6 UBR1
Entrez ID		8416	56901
HPRD ID		11938	14249
Ensembl ID		ENSG00000143412	ENSG00000185633
Uniprot IDs		O76027	Q9NRX3
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling SREBP Signaling Pathway Response To Sterol Depletion Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hydrolase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Positive Regulation Of Transcription, DNA-templated Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Stress Fiber Assembly Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Positive Regulation Of Gene Expression Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Regulation Of Stress Fiber Assembly Visual Behavior Neuron Death Platelet Degranulation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly	Regulation Of Mitochondrion Organization Negative Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Protein Linear Polyubiquitination Cellular Response To Leucine Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Queuosine Biosynthetic Process Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Cellular Protein Catabolic Process Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Protein Catabolic Process Ribonucleoprotein Complex Assembly Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Response To Leucine Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Dopamine Transport Aggresome Assembly Regulation Of Mitochondrial Fission Neurotransmitter Uptake Norepinephrine Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Actin Filament Bundle Assembly Synaptic Transmission, Dopaminergic Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Signaling Pathway Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?			apoeepsilon4 astrocyte astrocytes billion c3 capture carriers cd74 cingulate clarified clu coexpression contributions decades deficits differentially fastkd2 measureable microdissected pc posterior precuneus publicly reads resource storage transcriptome trmt61b weighted
Tagcloud (Difference) ?			apoeepsilon4 astrocyte astrocytes billion c3 capture carriers cd74 cingulate clarified clu coexpression contributions decades deficits differentially fastkd2 measureable microdissected pc posterior precuneus publicly reads resource storage transcriptome trmt61b weighted
Tagcloud (Intersection) ?