ODAD2 and OTUD1

		ODAD2	OTUD1
Description		outer dynein arm docking complex subunit 2	OTU deubiquitinase 1
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GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Cilium Axoneme Cell Projection Ciliary Base
	Molecular Function	Protein Binding	Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Cilium Movement Regulation Of Cilium Beat Frequency Determination Of Left/right Symmetry Heart Development Ventricular System Development Cell Projection Organization Outer Dynein Arm Assembly	Proteolysis Protein Deubiquitination Protein K63-linked Deubiquitination
Pathways			TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway
Drugs
Diseases
GWAS			Obesity (early onset extreme) ( 23563609) Tourette syndrome ( 30818990)
Interacting Genes		1 interacting genes: NR4A2	7 interacting genes: AKT1 CARD9 DCAF10 PRDX4 RIPK1 UBC YAP1
Entrez ID		55130	220213
HPRD ID		10663	19512
Ensembl ID		ENSG00000169126	ENSG00000165312
Uniprot IDs		A0A140VKF7 A0A5F9ZH22 B7Z7A1 B7Z7Y0 Q5T2S8	Q5VV17
PDB IDs		8J07	4BOP
Enriched GO Terms of Interacting Partners?		Habenula Development General Adaptation Syndrome 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Biosynthetic Process 1-phosphatidylinositol-5-phosphate 4-kinase Activity Maintenance Of Golgi Location Cellular Response To Corticotropin-releasing Hormone Stimulus 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate Metabolic Process	Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Lymphocyte Apoptotic Process T Cell Apoptotic Process Peptidyl-serine Phosphorylation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Organ Growth Negative Regulation Of Apoptotic Signaling Pathway Response To Ketone Negative Regulation Of Cilium Assembly Leukocyte Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Modification Process Apoptotic Signaling Pathway Protein Phosphorylation Regulation Of TRNA Methylation Enterocyte Differentiation Response To Oxidative Stress Phosphorylation Regulation Of Apoptotic Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Signaling Adaptor Activity Regulation Of Cilium Assembly Positive Regulation Of Protein Localization To Endoplasmic Reticulum Cytokine-mediated Signaling Pathway Regulation Of Notch Signaling Pathway Response To Insulin-like Growth Factor Stimulus Mammalian Oogenesis Stage Positive Regulation Of Gene Expression Protein Autophosphorylation TRNA (guanine-N7)-methylation Regulation Of Organ Growth Response To Tumor Necrosis Factor Cellular Response To Rapamycin Positive Regulation Of Defense Response Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Localization To Lysosome Positive Regulation Of Endodeoxyribonuclease Activity Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Localization To Nucleus Catabolic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-6-mediated Signaling Pathway Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Ripoptosome Assembly Death Domain Binding Ripoptosome Assembly Involved In Necroptotic Process
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