OTUD1

Gene Name		OTU deubiquitinase 1
Image
Gene Ontology Annotations	Cellular Component
	Molecular Function	Ubiquitin-specific Protease Activity
	Biological Process	Proteolysis Protein K63-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS		Obesity (early onset extreme) ( 23563609)
Protein-protein Interactions		2 interactors: RIPK1 UBC
Entrez ID		220213
HPRD ID		19512
Ensembl ID		ENSG00000165312
Uniprot IDs		Q5VV17
PDB IDs		4BOP
Enriched GO Terms of Interacting Partners?		TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway JNK Cascade Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of MAPK Activity Activation Of Innate Immune Response Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Regulation Of ATP:ADP Antiporter Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity MAPK Cascade Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Processing Regulation Of Innate Immune Response Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Necroptotic Process Positive Regulation Of Proteolysis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Apoptotic Signaling Pathway Amyloid Fibril Formation Positive Regulation Of Cytokine Production Positive Regulation Of MAPK Cascade Cytokine-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Necroptotic Signaling Pathway Peptidyl-serine Autophosphorylation Regulation Of Cytokine Production Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Positive Regulation Of Necrotic Cell Death Cellular Response To Growth Factor Stimulus Cellular Response To Cytokine Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor
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