CEP192 and SPIRE1

		CEP192	SPIRE1
Description		centrosomal protein 192	spire type actin nucleation factor 1
Image
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Procentriole Procentriole Replication Complex	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Cytosol Cytoskeleton Plasma Membrane Cell Cortex Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Phosphatase Binding	Actin Binding Protein Binding Microtubule Binding
	Biological Process	Centrosome Cycle Centriole Replication Response To Bacterium Centrosome Duplication Protein Localization To Centrosome Centrosome-templated Microtubule Nucleation Mitotic Spindle Assembly	Immune System Process Protein Transport Vesicle-mediated Transport Actin Cytoskeleton Organization Cleavage Furrow Formation Polar Body Extrusion After Meiotic Divisions Actin Nucleation Innate Immune Response Intracellular Transport Golgi Vesicle Transport Establishment Of Meiotic Spindle Localization Actin Filament Network Formation Formin-nucleated Actin Cable Assembly Positive Regulation Of Mitochondrial Fission Positive Regulation Of Double-strand Break Repair
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) General cognitive ability ( 29844566)	Carotid plaque burden ( 28282560) Hematocrit ( 32888494) Hemoglobin ( 32888494) Immune response to smallpox vaccine (IL-6) ( 22542470) Red blood cell count ( 32888494)
Interacting Genes		5 interacting genes: CIP2A LINC00839 PPP1CA SHBG UBC	1 interacting genes: BBS4
Entrez ID		55125	56907
HPRD ID		10855	11600
Ensembl ID		ENSG00000101639	ENSG00000134278
Uniprot IDs		Q8TEP8	J3KNG6 Q08AE8
PDB IDs		4N7Z 6FVI 6W3J 7PTB 8GUW 8PR7	2YLE 2YLF 3R7G 3RBW
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Promoter Clearance Regulation Of Glycogen Catabolic Process Positive Regulation Of Termination Of DNA-templated Transcription Glycogen Granule Positive Regulation Of Termination Of RNA Polymerase II Transcription PTW/PP1 Phosphatase Complex RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Androgen Binding Mitochondrial Outer Membrane Meiotic Cytokinesis Formin-nucleated Actin Cable Assembly Parallel Actin Filament Bundle Assembly Establishment Of Meiotic Spindle Localization Polar Body Extrusion After Meiotic Divisions Cleavage Furrow Formation Actin Filament Network Formation Broken Chromosome Clustering	Pericentriolar Material Protein Localization To Centrosome Protein Localization To Cytoskeleton Centrosome Cycle Microtubule Organizing Center Organization Centrosome-templated Microtubule Nucleation Centriole RNA Polymerase II-specific DNA-binding Transcription Factor Binding Procentriole Sensory Processing Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Microtubule Nucleation By Microtubule Organizing Center Protein Localization To Photoreceptor Outer Segment Procentriole Replication Complex BBSome PML Body Organization Microtubule Anchoring At Centrosome Protein Localization To Non-motile Cilium Retinal Rod Cell Development Negative Regulation Of Appetite Fat Pad Development Erythrocyte Homeostasis Leptin-mediated Signaling Pathway Regulation Of Non-motile Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Establishment Of Melanosome Localization Regulation Of Response To Food Sperm Flagellum Assembly Regulation Of Cilium Beat Frequency Photoreceptor Cell Outer Segment Organization Melanosome Localization Microtubule Cytoskeleton Organization Response To Leptin Brain Morphogenesis Microtubule Anchoring Striatum Development Melanosome Transport Ventricular System Development Face Development Pigment Granule Transport Dynactin Binding Retina Homeostasis Microtubule Anchoring At Microtubule Organizing Center Regulation Of Appetite Negative Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Nuclear Body Organization Reproductive System Development Phosphatidylinositol-5-phosphate Binding Centriole Replication
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?