TAPBPL and KRT35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TAPBPL	KRT35
Description		TAP binding protein like	keratin 35
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane MHC Class I Peptide Loading Complex	Extracellular Space Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding MHC Class I Protein Complex Binding TAP Complex Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Immune System Process Peptide Antigen Assembly With MHC Class I Protein Complex Negative Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I	Morphogenesis Of An Epithelium Anatomical Structure Morphogenesis Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		14 interacting genes: ADAMTSL4 CYSRT1 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 NBPF19 NOTCH2NLA PM20D2 TCF4 TEPSIN	88 interacting genes: ABI3 AIRIM ATG9A BCAS2 C21orf58 CCDC120 CCDC185 CCDC196 CCHCR1 CD33 CTSZ DMRT3 DTNB EFCAB3 ENKD1 EXOSC5 FAM221B FRS3 HAPLN2 HCK HDAC4 HGS HOXA1 HOXC8 KCTD9 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LENG1 LGALS14 LONRF1 MAPKBP1 MCRS1 MYO15B OIP5 OTX1 PKN1 POU4F2 PRPF18 PRPF31 PRR35 RUNX1T1 SCNM1 SHC3 SLC43A2 SMARCE1 SMYD1 TAPBPL TBC1D21 TBC1D30 TBC1D7 TCEANC TCHP TEKT4 TEPSIN TLE5 TRIM29 TSG101 TXLNA TXLNB UBASH3A USP2 VPS9D1 ZNF417 ZNF446
Entrez ID		55080	3886
HPRD ID		06153	04138
Ensembl ID		ENSG00000139192	ENSG00000197079
Uniprot IDs		Q9BX59	Q92764
PDB IDs		5WER 7RNO 9C96
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Morphogenesis Of An Epithelium Epidermis Development Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Pigment Cell Development Para-aminobenzoyl-glutamate Hydrolase Activity Coated Vesicle Membrane Identical Protein Binding Folic Acid Catabolic Process Beta-catenin-TCF7L2 Complex TFIIB-class Transcription Factor Binding Cellular Developmental Process Interstitial Matrix Cytoskeleton Organization Cell Differentiation	Structural Constituent Of Skin Epidermis Keratin Filament Keratinization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Epidermis Development Intermediate Filament Cytoskeleton Cornified Envelope Negative Regulation Of Cilium Assembly Regulation Of Organelle Assembly Extracellular Exosome
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