NRDE2 and RCOR3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NRDE2	RCOR3
Description		NRDE-2, necessary for RNA interference, domain containing	REST corepressor 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck	Histone Deacetylase Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Protein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	Mitotic Cell Cycle MRNA Processing DNA Damage Response RNA Splicing Regulatory NcRNA-mediated Heterochromatin Formation Positive Regulation Of RNA Export From Nucleus MRNA Stabilization Cell Division Negative Regulation Of RNA Catabolic Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Plateletcrit ( 32888494)
Interacting Genes		11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28	73 interacting genes: ABI1 ANKRD11 APP BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GPRASP3 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		55051	55758
HPRD ID		12625	08338
Ensembl ID		ENSG00000119720	ENSG00000117625
Uniprot IDs		Q9H7Z3	Q9P2K3
PDB IDs		6IEH	4CZZ
Enriched GO Terms of Interacting Partners?			Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Protein Binding Identical Protein Binding Supramolecular Fiber Organization Microtubule TORC1 Complex Assembly Cytoskeleton Organization Epithelial Cell Differentiation Microtubule-based Process Telomeric DNA Binding Centrosome
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