PLPPR1 and ERP44

		PLPPR1	ERP44
Description		phospholipid phosphatase related 1	endoplasmic reticulum protein 44
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Membrane Cell Projection Neuron Projection	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidate Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Phospholipid Metabolic Process Signal Transduction Nervous System Development Phospholipid Dephosphorylation	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis
Pathways		Lysosphingolipid and LPA receptors	Neutrophil degranulation
Drugs
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Hip circumference adjusted for BMI ( 28552196) Triglyceride levels in HIV infection ( 33109212)	Preeclampsia ( 23551011)
Interacting Genes		5 interacting genes: LEPROT PLN SERP1 SLC30A2 TMPPE	3 interacting genes: ERO1A ERO1B ITPR1
Entrez ID		54886	23071
HPRD ID		17906	10290
Ensembl ID		ENSG00000148123	ENSG00000023318
Uniprot IDs		Q8TBJ4	A0A384MEE7 Q9BS26
PDB IDs			2R2J 5GU6 5GU7 5HQP 5XWM
Enriched GO Terms of Interacting Partners?		Response To Zinc Ion Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Mitochondrion Zinc Ion Import Into Secretory Vesicle Response To Unfolded Protein Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cellular Homeostasis Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Zinc Export Across Plasma Membrane Circadian Sleep/wake Cycle Process Vacuolar Transport Zinc Ion Import Into Lysosome ATPase Inhibitor Activity Zinc:proton Antiporter Activity Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Transporter Inhibitor Activity Regulation Of Relaxation Of Cardiac Muscle G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Cardiac Muscle Cell Membrane Potential Sleep Vacuolar Transmembrane Transport Response To Endoplasmic Reticulum Stress Muscle Organ Morphogenesis Secretory Vesicle Positive Regulation Of Growth Hormone Secretion Negative Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of ATP-dependent Activity Locomotor Rhythm Endoplasmic Reticulum Membrane Negative Regulation Of Heart Rate Endosome Membrane Zinc Ion Import Into Organelle Negative Regulation Of Protein Localization To Cell Surface Regulation Of Growth Hormone Receptor Signaling Pathway Relaxation Of Cardiac Muscle Regulation Of Growth Hormone Secretion Negative Regulation Of Calcium Ion Import Positive Regulation Of Establishment Of Protein Localization Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Response To Metal Ion Regulation Of Relaxation Of Muscle Zymogen Granule Membrane Monoatomic Cation Transmembrane Transporter Activity Relaxation Of Muscle Circadian Behavior	Calcineurin Complex Thiol Oxidase Activity Protein Folding In Endoplasmic Reticulum Protein-disulfide Reductase Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cell Redox Homeostasis FAD Binding Endoplasmic Reticulum Membrane Sphingolipid Floppase Activity Release Of Sequestered Calcium Ion Into Cytosol Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Negative Regulation Of Sequestering Of Calcium Ion Response To Vitamin B3 Positive Regulation Of High-density Lipoprotein Particle Assembly Apolipoprotein A-I Receptor Activity Cytoskeletal Calyx Endoplasmic Reticulum-Golgi Intermediate Compartment Organization
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