CRCT1 and LCE1D

Number of citations of the paper that reports this interaction (PubMedID 36949045)
82

Data Source:
BioGRID (two hybrid)

		CRCT1	LCE1D
Description		cysteine rich C-terminal 1	late cornified envelope 1D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cornified Envelope Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Epidermis Development Keratinization Cognition Cellular Response To Calcium Ion
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 21804549 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 26482879) Obesity-related traits ( 23251661) Plantar warts ( 28928442)	Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		62 interacting genes: AGTRAP ALPP APLP1 CEP126 CHD3 CYP21A2 CYSRT1 EEF1A1 GRN IGSF21 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-8 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1C LCE1D LCE1F LCE2A LCE2B LCE2C LCE3A LCE4A LRIF1 MACO1 MEOX2 NOTCH2NLA NUP62 OIT3 PLSCR4 PTN RGS17 RGS20 SDCBP2 SLC39A7 TGM1 TLE1 TRIM55 TRIM63 VIM VWC2L	69 interacting genes: ADAMTSL4 ALPP AMOT CATSPER1 CHIC2 CRCT1 CYP21A2 CYSRT1 FBLN1 GRN HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE4A LCE5A MACO1 MDFI MEOX2 NBPF19 NOTCH2NLA NTAQ1 NUFIP2 PCSK5 PIAS4 RAD54L2 RGS17 RGS20 RNF4 SCARF1 SMCP SPRY1 TGFB1 TRIM42 UBE2I
Entrez ID		54544	353134
HPRD ID		16635	13968
Ensembl ID		ENSG00000169509	ENSG00000172155
Uniprot IDs		Q9UGL9	Q5T752
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development Hair Cycle Tissue Development Identical Protein Binding Protein Binding Positive Regulation Of Axon Regeneration	Intermediate Filament Keratin Filament Epidermis Development Keratinization Hair Cycle Tissue Development Identical Protein Binding Protein Binding Negative Regulation Of Protein Localization To Chromatin
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