PPIL3 and MAIP1

		PPIL3	MAIP1
Description		peptidylprolyl isomerase like 3	matrix AAA peptidase interacting protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex Catalytic Step 2 Spliceosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Isomerase Activity	Protein Binding Ribosome Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing Protein Folding RNA Splicing	Protein Insertion Into Mitochondrial Inner Membrane From Matrix Calcium Import Into The Mitochondrion Protein Insertion Into Mitochondrial Membrane Mitochondrial Calcium Ion Homeostasis
Pathways		mRNA Splicing - Major Pathway	Processing of SMDT1
Drugs
Diseases
GWAS		Breast cancer ( 27117709) Breast cancer (estrogen-receptor negative) ( 27117709) Triptolide cytotoxicity ( 26121980)	Bipolar disorder lithium response (continuous) or schizophrenia ( 29121268) Sleep duration ( 30846698)
Interacting Genes		10 interacting genes: CENATAC DMRTB1 PCBP1 PHC1 RPS13 SHARPIN SLU7 TAB2 TAB3 YTHDF1	5 interacting genes: APOC1 APOC2 APOC4 APP H4C7
Entrez ID		53938	79568
HPRD ID		15163	07994
Ensembl ID		ENSG00000240344	ENSG00000162972
Uniprot IDs		A0A024R3V4 A0A0S2Z5A8 Q9H2H8	Q8WWC4
PDB IDs		1XYH 2OJU 2OK3 8C6J
Enriched GO Terms of Interacting Partners?			High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Lipoprotein Metabolic Process Acylglycerol Homeostasis Triglyceride Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Intermediate-density Lipoprotein Particle Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Regulation Of Receptor-mediated Endocytosis Chylomicron Phospholipid Efflux Low-density Lipoprotein Particle Negative Regulation Of Lipoprotein Particle Clearance Lipid Homeostasis Negative Regulation Of Cholesterol Transport Molecular Function Activator Activity Plasma Lipoprotein Particle Clearance Cholesterol Efflux Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process Chemical Homeostasis Regulation Of Fatty Acid Biosynthetic Process Lipid Transport Regulation Of Endocytosis Regulation Of Small Molecule Metabolic Process Regulation Of Lipid Catabolic Process Regulation Of Cholesterol Transport Cholesterol Transport Negative Regulation Of Endocytosis Sterol Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Phospholipid Transport Homeostatic Process Regulation Of Fatty Acid Metabolic Process Negative Regulation Of Lipid Metabolic Process Protein-containing Complex Organization Regulation Of Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process
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