SERPINA4 and YAE1D1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SERPINA4	YAE1D1
Gene Name		serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	Yae1 domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS		Vaspin levels ( 22907691)
Protein-Protein Interactions		13 interactors: CTSD GADD45G ILK KLK1 KLK2 MAP4K2 MAPK6 NR4A1 RASA1 TAB1 TNFRSF14 TNNT1 YAE1D1	17 interactors: APP BBS10 CHD3 CRMP1 HAUS5 HNRNPA2B1 KIAA1377 MCF2L METTL18 NACAD NAT14 ORAOV1 SERPINA4 SLC25A33 TPD52L1 VIM ZNF579
Entrez ID		5267	57002
HPRD ID		01004	16669
Ensembl ID		ENSG00000100665	ENSG00000241127
Uniprot IDs		P29622	B4DE83 Q9NRH1
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of MAPKKK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Phosphorylation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Transferase Activity Positive Regulation Of Cellular Protein Metabolic Process Intracellular Signal Transduction Positive Regulation Of MAP Kinase Activity MAPK Cascade Regulation Of Cellular Protein Metabolic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Activation Of Protein Kinase Activity Regulation Of Protein Metabolic Process Signal Transduction By Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cellular Metabolic Process JNK Cascade Extracellular Matrix Disassembly Regulation Of Intracellular Signal Transduction Stress-activated MAPK Cascade Regulation Of Cell-matrix Adhesion Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Locomotion Positive Regulation Of Signal Transduction Immune System Process Immune Response Regulation Of JNK Cascade Regulation Of Cell Adhesion Defense Response	Spindle Organization
Tagcloud ?		academic bcl2 beadchip caucasian cohorts complicates diego discovery entirely genotyped genotyping hundred illumina injury kallistatin kidney nucleotide polymorphisms predicts rs12457893 rs8094315 san septic shock sixty split tertiary thousand validation
Tagcloud (Difference) ?		academic bcl2 beadchip caucasian cohorts complicates diego discovery entirely genotyped genotyping hundred illumina injury kallistatin kidney nucleotide polymorphisms predicts rs12457893 rs8094315 san septic shock sixty split tertiary thousand validation
Tagcloud (Intersection) ?