PFKP and LINC00632

Number of citations of the paper that reports this interaction (PubMedID 36527092)
63

Data Source:
BioGRID (unspecified method)

		PFKP	LINC00632
Description		phosphofructokinase, platelet	long intergenic non-protein coding RNA 632
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol 6-phosphofructokinase Complex Membrane Extracellular Exosome
	Molecular Function	Nucleotide Binding Catalytic Activity 6-phosphofructokinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Identical Protein Binding Protein-containing Complex Binding Cadherin Binding Metal Ion Binding Fructose-6-phosphate Binding
	Biological Process	Fructose 6-phosphate Metabolic Process Glycolytic Process Fructose 1,6-bisphosphate Metabolic Process Canonical Glycolysis Cellular Response To Leukemia Inhibitory Factor
Pathways		Glycolysis
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Body size at age 10 ( 32376654) Disc degeneration (lumbar) ( 22993228) HDL cholesterol levels in HIV infection ( 33109212) Hippocampal volume in mild cognitive impairment ( 29274321) Mean platelet volume ( 32888494) Scalp hair shape ( 26926045) Subclinical trait of interstitial lung disease (percentage of high attenuation areas on CT scan) ( 28521775)
Interacting Genes		15 interacting genes: ACD AGO2 AKT1 DYNLL1 EGFR KAT5 LINC00632 NUTF2 POT1 SUMO2 TERF1 TINF2 TRIM21 VHL WNK1	37 interacting genes: ACO2 ACTR2 ANP32A ANXA6 ARF3 ASPH CTSB DYNC1LI2 ELAVL1 GDI1 GDI2 GNB1 HSPE1 ITGA3 LAP3 LGALS3 LMAN1 MDH2 MXRA7 PAICS PFKP PGD PGRMC1 PGRMC2 PSMA1 PXN RAB1B RECQL RPLP0 RPN2 RRAS2 SF1 STMN1 TGFBI TPM1 TUBA1C UGDH
Entrez ID		5214	286411
HPRD ID		01384
Ensembl ID		ENSG00000067057	ENSG00000203930
Uniprot IDs		A0A7I2V3Z0 A0A8V8TMY4 B1APP6 Q01813
PDB IDs		4RH3 4U1R 4WL0 4XYJ 4XYK 4XZ2 7TFF
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly Regulation Of DNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Macromolecule Metabolic Process Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Regulation Of DNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process RNA-templated DNA Biosynthetic Process Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of Telomere Maintenance Positive Regulation Of Metabolic Process Positive Regulation Of Organelle Organization Telomere Organization Positive Regulation Of Cell Cycle Establishment Of Protein Localization To Organelle Regulation Of Establishment Of Protein Localization To Telomere Organelle Organization Activation-induced Cell Death Of T Cells Regulation Of Autophagy Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Regulation Of Primary Metabolic Process Negative Regulation Of Catabolic Process Chromosome, Telomeric Region Nitric-oxide Synthase Regulator Activity Chromosome Telomeric D-loop Disassembly DNA Metabolic Process Positive Regulation Of Cellular Component Organization	Extracellular Exosome Focal Adhesion Rab GDP-dissociation Inhibitor Activity
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