STK26 and PDCD10

Number of citations of the paper that reports this interaction (PMID 23455922)
9

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		STK26	PDCD10
Gene Name		serine/threonine protein kinase 26	programmed cell death 10
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Golgi-associated Vesicle Centrosome Cytosol Apical Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Cell Periphery	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Homodimerization Activity	Protein Binding Protein Kinase Binding Protein Homodimerization Activity Protein N-terminus Binding
	Biological Process	Protein Phosphorylation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Microvillus Assembly Response To Hydrogen Peroxide Regulation Of Apoptotic Process Protein Autophosphorylation Regulation Of Hydrogen Peroxide-induced Cell Death	Angiogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Rho Protein Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Response To Hydrogen Peroxide Negative Regulation Of Apoptotic Process Stress Fiber Assembly Positive Regulation Of MAP Kinase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Notch Signaling Pathway Protein Stabilization Establishment Of Golgi Localization Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Golgi Reassembly Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: APP GOLGA2 MBP NEDD4 PDCD10 RAF1 SRPK1	5 interactors: C4orf19 CHMP5 STK24 STK25 STK26
Entrez ID		51765	11235
HPRD ID		06663	10141
Ensembl ID		ENSG00000134602	ENSG00000114209
Uniprot IDs		B4E0Y9 Q8NBY1 Q9P289	Q9BUL8
PDB IDs		3GGF 3W8I 4FZA 4FZD 4FZF 4GEH	3AJM 3L8I 3L8J 3RQE 3RQF 3RQG 3W8H 3W8I 4GEH
Enriched GO Terms of Interacting Partners?		Immune Response Response To Stress Neuromuscular Junction Development Immune System Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Metabolic Process Locomotion Response To Inorganic Substance Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Death-inducing Signaling Complex Assembly Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Cellular Ketone Metabolic Process Defense Response Regulation Of Synapse Structure Or Activity Regulation Of Neuron Differentiation Regulation Of Peptidyl-serine Phosphorylation Anatomical Structure Development Wound Healing Generation Of Neurons Regulation Of Cell Differentiation Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Synaptic Growth At Neuromuscular Junction Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Neurogenesis Cell Activation Regulation Of Protein Binding Response To Wounding Regulation Of Neurogenesis Defense Response To Nematode Collateral Sprouting In Absence Of Injury Developmental Process Negative Regulation Of Cell Differentiation Regulation Of Protein Kinase Activity Cell Development Cell Differentiation Signaling Synapse Organization Golgi Reassembly Cell Communication Regulation Of Kinase Activity Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Negative Regulation Of Neuron Differentiation Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition Intracellular Receptor Signaling Pathway	Response To Hydrogen Peroxide Response To Reactive Oxygen Species Protein Autophosphorylation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Oxidative Stress Response To Inorganic Substance Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Apoptotic Process Programmed Cell Death Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Cell Death Death Intrinsic Apoptotic Signaling Pathway Cellular Response To Oxidative Stress Golgi Reassembly Protein Phosphorylation Signal Transduction By Phosphorylation Establishment Of Golgi Localization Establishment Of Organelle Localization Golgi Inheritance Apoptotic Signaling Pathway Regulation Of Mitotic Spindle Assembly Regulation Of Neuron Projection Development Golgi Localization Regulation Of Spindle Assembly Organelle Localization Phosphorylation Regulation Of Cellular Component Organization Regulation Of Hydrogen Peroxide-induced Cell Death Regulation Of Mitotic Spindle Organization Regulation Of Cell Projection Organization Microvillus Assembly Microvillus Organization Regulation Of Neuron Differentiation Regulation Of Axon Regeneration Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Regulation Of Receptor Recycling Regulation Of Neurogenesis Regulation Of Response To Reactive Oxygen Species Endosome To Lysosome Transport Metaphase Plate Congression Phosphate-containing Compound Metabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Development Lysosomal Transport Regulation Of Centrosome Cycle Regulation Of Cellular Response To Oxidative Stress
Tagcloud ?			4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 personalised psmb1 rmnd5a runt runx2 sacm1l subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Difference) ?			4b adriamycin ataxia carboplatin coded ct cyclophosphamide desirable eif4b isoaspartate matr3 matrin meiotic microrchidia morc3 pbl pbls pcmtd2 personalised psmb1 rmnd5a runt runx2 sacm1l subtraction telangiectasia tmem66 undesired znf644
Tagcloud (Intersection) ?