GPRC5B and C11orf71

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GPRC5B	C11orf71
Gene Name		G protein-coupled receptor, class C, group 5, member B	chromosome 11 open reading frame 71
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Binding G-protein Coupled Receptor Activity Protein Kinase Binding Protein Kinase Activator Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Locomotory Behavior Positive Regulation Of Neuron Projection Development Glucose Homeostasis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neuron Differentiation Positive Regulation Of Inflammatory Response Positive Regulation Of Macrophage Cytokine Production Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Obesity ( 23563607) Obesity-related traits ( 23251661)	Asthma ( 21804549)
Protein-Protein Interactions		2 interactors: ADRB2 C11orf71	3 interactors: APP DKKL1 GPRC5B
Entrez ID		51704	54494
HPRD ID		16177	07874
Ensembl ID		ENSG00000167191	ENSG00000180425
Uniprot IDs		B7Z2G0 B7Z440 Q9NZH0	Q6IPW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Heat Generation Diet Induced Thermogenesis Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Negative Regulation Of Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Response To Dietary Excess Negative Regulation Of Multicellular Organism Growth Negative Regulation Of Muscle Contraction Negative Regulation Of Systemic Arterial Blood Pressure Temperature Homeostasis Activation Of Adenylate Cyclase Activity Endosome To Lysosome Transport Vasodilation Bone Resorption Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Brown Fat Cell Differentiation Lysosomal Transport Regulation Of Vasodilation Positive Regulation Of Lyase Activity Negative Regulation Of Blood Pressure Regulation Of Smooth Muscle Contraction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Adenylate Cyclase Activity Response To Cold Bone Remodeling Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Regulation Of Sodium Ion Transport Positive Regulation Of CAMP Metabolic Process Regulation Of Bone Mineralization Regulation Of Blood Vessel Size Regulation Of Tube Size Vacuolar Transport Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Developmental Growth Regulation Of CAMP Biosynthetic Process Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Ossification Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Binding Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process Tissue Remodeling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway	Regulation Of Protein Tyrosine Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Synaptic Growth At Neuromuscular Junction Locomotory Behavior Regulation Of Cell Differentiation Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Cellular Amino Acid Metabolic Process Neuron Remodeling Regulation Of Cellular Ketone Metabolic Process Regulation Of Neuron Differentiation Behavior Positive Regulation Of Macrophage Cytokine Production Cellular Copper Ion Homeostasis Regulation Of Neurogenesis Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Kinase Activity Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cell Development Positive Regulation Of Cell Differentiation Chemical Homeostasis Positive Regulation Of Protein Tyrosine Kinase Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Positive Regulation Of Cytokine Production Involved In Immune Response Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Cellular Protein Metabolic Process Axon Cargo Transport Mating Positive Regulation Of Fat Cell Differentiation Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Protein Metabolic Process
Tagcloud ?		angiogenesis coitus coupled crucial embryonic endothelial fetal fibroblast gestation glycogen homeostasis immunohistochemical localization maternal matrix morphogenesis mrnas murine orphan physiological placenta ra raralpha reproductive retinoic sac stromal vascular yolk
Tagcloud (Difference) ?		angiogenesis coitus coupled crucial embryonic endothelial fetal fibroblast gestation glycogen homeostasis immunohistochemical localization maternal matrix morphogenesis mrnas murine orphan physiological placenta ra raralpha reproductive retinoic sac stromal vascular yolk
Tagcloud (Intersection) ?