GPRC5B

Gene Name		G protein-coupled receptor, class C, group 5, member B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nucleolus Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Binding G-protein Coupled Receptor Activity Protein Kinase Binding Protein Kinase Activator Activity
	Biological Process	G-protein Coupled Receptor Signaling Pathway Locomotory Behavior Positive Regulation Of Neuron Projection Development Glucose Homeostasis Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Neuron Differentiation Positive Regulation Of Inflammatory Response Positive Regulation Of Macrophage Cytokine Production Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Obesity ( 23563607) Obesity-related traits ( 23251661)
Protein-protein Interactions		2 interactors: ADRB2 C11orf71
Entrez ID		51704
HPRD ID		16177
Ensembl ID		ENSG00000167191
Uniprot IDs		B7Z2G0 B7Z440 Q9NZH0
PDB IDs
Enriched GO Terms of Interacting Partners?		Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure Heat Generation Diet Induced Thermogenesis Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Negative Regulation Of Smooth Muscle Contraction Adrenergic Receptor Signaling Pathway Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Response To Dietary Excess Negative Regulation Of Multicellular Organism Growth Negative Regulation Of Muscle Contraction Negative Regulation Of Systemic Arterial Blood Pressure Temperature Homeostasis Activation Of Adenylate Cyclase Activity Endosome To Lysosome Transport Vasodilation Bone Resorption Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Brown Fat Cell Differentiation Lysosomal Transport Regulation Of Vasodilation Positive Regulation Of Lyase Activity Negative Regulation Of Blood Pressure Regulation Of Smooth Muscle Contraction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Protein Binding Regulation Of Adenylate Cyclase Activity Response To Cold Bone Remodeling Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Regulation Of Sodium Ion Transport Positive Regulation Of CAMP Metabolic Process Regulation Of Bone Mineralization Regulation Of Blood Vessel Size Regulation Of Tube Size Vacuolar Transport Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Developmental Growth Regulation Of CAMP Biosynthetic Process Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Ossification Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Binding Regulation Of Multicellular Organism Growth Regulation Of CAMP Metabolic Process Tissue Remodeling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Tagcloud ?		angiogenesis coitus coupled crucial embryonic endothelial fetal fibroblast gestation glycogen homeostasis immunohistochemical localization maternal matrix morphogenesis mrnas murine orphan physiological placenta ra raralpha reproductive retinoic sac stromal vascular yolk