C11orf71 and DKKL1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		C11orf71	DKKL1
Description		chromosome 11 open reading frame 71	dickkopf like acrosomal protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Extracellular Region Extracellular Space Cytoplasmic Vesicle
	Molecular Function		Co-receptor Binding Receptor Antagonist Activity
	Biological Process		Penetration Of Zona Pellucida Anatomical Structure Morphogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of Fat Cell Differentiation Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Testosterone Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 21804549 29273806)	Multiple sclerosis ( 21833088 24076602)
Interacting Genes		3 interacting genes: APP DKKL1 GPRC5B	2 interacting genes: C11orf71 FJX1
Entrez ID		54494	27120
HPRD ID		07874	10396
Ensembl ID		ENSG00000180425	ENSG00000104901
Uniprot IDs		A0A0A8K8C2 Q6IPW1	A0A140VK15 Q9UK85
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Neuron Differentiation G Protein-coupled Receptor Binding Cytoplasmic Vesicle Positive Regulation Of Cell Differentiation Acetylcholine Receptor Activator Activity Membrane Raft PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Inflammatory Response Regulation Of Neuron Differentiation Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Positive Regulation Of Developmental Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Receptor Complex Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Testosterone Biosynthetic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Extracellular Space Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Cell Differentiation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Phosphate Metabolic Process NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Small Molecule Metabolic Process Axon Choice Point Recognition	Retina Layer Formation
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