FKBP7 and RBM45

		FKBP7	RBM45
Description		FKBP prolyl isomerase 7	RNA binding motif protein 45
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleus Nucleoplasm Cytoplasm Ribonucleoprotein Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding Identical Protein Binding
	Biological Process		Nervous System Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)	Refractive error ( 32231278)
Interacting Genes		107 interacting genes: ABHD16A ADGRE2 ADIPOQ AP1M1 APOD ASPH BET1 BMP10 BRICD5 C3orf52 CD81 CDIPT CDS2 CERCAM CFTR CIAO2A CLCA4 CLDN19 CNIH1 CTSA CXCL16 CYB561D2 CYB5B DIABLO ERMP1 FAM3C FARS2 GET3 H4C7 HHATL HMOX1 HSBP1L1 HTATIP2 IER3 IFITM3 IGFBP5 IRF2 JOSD2 LAT LNPEP MAN2B2 MIEF2 MRM1 NFU1 NKG7 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX16 PEX19 PLLP PLP1 PLP2 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SELENOK SERP1 SGTA SLC30A3 SLC38A7 SLC7A14 SNX1 SNX12 STATH STX7 STX8 SUCLA2 TARS2 TCP11X2 TECR TF THAP4 THSD7B TMEM108 TMEM120B TMEM147 TMEM14A TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TSPO2 TTPA TXNDC12 UBIAD1 UBQLN4 UNC93B1 UPK1B UPK2 VSTM4 WFDC2 WIPI2 YIPF4 YIPF6 ZFPL1	16 interacting genes: ALX1 FANCL FXR1 FXR2 MEMO1 MIR15B MIR200A MIR205 MIR25 MIR29A MIR34B NTAQ1 OGT TNPO2 TRAF1 TXN2
Entrez ID		51661	129831
HPRD ID		08451	09927
Ensembl ID		ENSG00000079150	ENSG00000155636
Uniprot IDs		B4DRE2 Q9Y680	Q8IUH3
PDB IDs			7CSX 7CSZ 8WQ3 8WQ5
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein Binding Chloride Channel Inhibitor Activity Regulation Of Cellular Localization Cellular Localization Protein Insertion Into ER Membrane Transferrin Receptor Binding Alkenylglycerophosphocholine Hydrolase Activity Lysosome Peroxisome Membrane Biogenesis Intraciliary Transport Particle B Binding Cholesterol Binding Establishment Of Localization In Cell	MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex Negative Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Translation Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Translation Negative Regulation Of Developmental Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Developmental Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Endothelial Cell Migration Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement MRNA Destabilization RNA Destabilization Translation Regulator Activity Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of MRNA Catabolic Process Positive Regulation Of Tissue Remodeling Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Regulation Of Multicellular Organismal Development Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Negative Regulation Of Amyloid-beta Formation Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Cell Motility Negative Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Regulation Of Endothelial Cell Proliferation Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?