TMBIM4 and VENTX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMBIM4	VENTX
Description		transmembrane BAX inhibitor motif containing 4	VENT homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	Calcium Channel Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Apoptotic Process Locomotory Behavior Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Calcium-mediated Signaling Calcium Ion Transmembrane Transport	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Senescence-Associated Secretory Phenotype (SASP) Transcriptional Regulation by VENTX
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 28498854)
Interacting Genes		4 interacting genes: POGZ SLC22A1 VENTX VKORC1	93 interacting genes: ABHD11 ACTMAP ADAMTSL4 ARID5A ARSA ATXN7L1 BATF2 BHLHE40 C10orf55 C1orf94 C6orf15 CEACAM6 CERCAM CES1 CFP CREM CSN3 CTAG1A CTAG1B CYSRT1 DAB1 DAZAP2 FAM168B FAM86C1P GLIS2 HOXC8 HYPK INTS11 IRF9 ITIH6 KRT34 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP22-1 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LITAF LYG1 MAGED1 MIEN1 ODAM PLA2G2F PLEKHB1 POU6F2 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RBPMS RHOXF2 RNF144B RNF4 ROR2 RSKR SLC15A2 SMUG1 SOX14 SPRY4 SYNGAP1 TBX15 TBX19 TBX22 TEKT5 TLE2 TMBIM4 TMEM42 TRIP13 TSC1 UBAP2 UBE2I UBQLN2 USP54 VAC14 VHLL WWOX YPEL3 ZBTB32 ZNF34
Entrez ID		51643	27287
HPRD ID		13032	06197
Ensembl ID		ENSG00000155957	ENSG00000151650
Uniprot IDs		G3V1M2 G3XAA5 Q7Z782 Q9HC24	O95231
PDB IDs
Enriched GO Terms of Interacting Partners?		(R)-carnitine Transmembrane Transport Acetylcholine Transport Xenobiotic Metabolic Process Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity Metanephric Proximal Tubule Development Epinephrine Transport Norepinephrine:sodium Symporter Activity (R)-carnitine Transport Spermidine Transmembrane Transport Putrescine Transport Dopamine:sodium Symporter Activity Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity O-acyl-L-carnitine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Carnitine Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Proximal Tubule Development Carnitine Transmembrane Transport Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Amino-acid Betaine Transport Quaternary Ammonium Group Transport Catecholamine Uptake Dopamine Uptake Prostaglandin Transport Serotonin Transport Metanephric Nephron Tubule Development Pyrimidine-containing Compound Transmembrane Transport Kinetochore Assembly Quinone Binding Vitamin K Metabolic Process	Intermediate Filament Keratin Filament Protein Binding
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