PDGFRL and ZNF510

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		PDGFRL	ZNF510
Description		platelet derived growth factor receptor like	zinc finger protein 510
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region	Nucleus
	Molecular Function	Platelet Activating Factor Receptor Activity Platelet-derived Growth Factor Receptor Activity Platelet-derived Growth Factor Beta-receptor Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Platelet-derived Growth Factor Receptor-beta Signaling Pathway Cellular Response To Platelet-derived Growth Factor Stimulus Platelet-derived Growth Factor Receptor Signaling Pathway	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Hippocampal volume in normal cognition ( 29274321) Placental abruption ( 29884306) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma parathyroid hormone levels ( 30134803) Spatial memory ( 31596458) Sphingomyelin 24:0 levels ( 31560688)
Interacting Genes		24 interacting genes: ASPH BAAT CCDC180 CTSV FANCC FBP2 HRAS MAP2K1 MAPK12 MAPK3 MBP NANS PFKM PPP2CB PPP3R2 RANGAP1 SFRP4 SMAD1 SPARCL1 TBC1D2 TGFB1 TMEM129 XPA ZNF510	21 interacting genes: APC AURKA BRAF BUB1 CCND1 CDH1 CTNNA1 DLC1 EGFR FBXW7 MLH3 MSH2 ODC1 PDGFRL PTPN12 PTPRJ SMAD1 SMAD2 SMAD4 STK11 TGFBR2
Entrez ID		5157	22869
HPRD ID		05206	18348
Ensembl ID		ENSG00000104213	ENSG00000081386
Uniprot IDs		Q15198	Q6NUI8 Q9Y2H8
PDB IDs
Enriched GO Terms of Interacting Partners?		Myelination Axon Ensheathment MAPK Cascade Regulation Of Intracellular Transport Glial Cell Development Schwann Cell Development Regulation Of Cellular Localization Regulation Of Golgi Inheritance Intracellular Signaling Cassette Trachea Formation Regulation Of Intracellular Protein Transport Fructose 1,6-bisphosphate Metabolic Process ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Regulation Of Establishment Of Protein Localization Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Catalytic Activity Bergmann Glial Cell Differentiation Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of ERK1 And ERK2 Cascade Chemical Homeostasis Cytosol Fructose 6-phosphate Metabolic Process Negative Regulation Of Immune Response To Tumor Cell Negative Regulation Of Cell-cell Adhesion Regulation Of Transport Regulation Of Protein Localization MAP Kinase Activity Positive Regulation Of Intracellular Protein Transport Regulation Of MiRNA Metabolic Process Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Golgi Organization Regulation Of Early Endosome To Late Endosome Transport Homeostatic Process Negative Regulation Of Transport Regulation Of Protein Transport Hematopoietic Or Lymphoid Organ Development Positive Regulation Of Protein Transport Animal Organ Formation Face Development Negative Regulation Of Cell Population Proliferation ERBB2 Signaling Pathway Intracellular Signal Transduction Gland Development Positive Regulation Of Hydrolase Activity Muscle Cell Cellular Homeostasis Regulation Of Protein Localization To Synapse Lung Morphogenesis	Gamma-catenin Binding Animal Organ Development Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis SMAD Protein Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Cell Differentiation SMAD Protein Complex Response To Growth Factor Cell Population Proliferation Heteromeric SMAD Protein Complex Developmental Process Regulation Of Protein Catabolic Process Intracellular Signal Transduction Secondary Palate Development Cell Surface Receptor Signaling Pathway Regulation Of Cell Cycle Phase Transition Regulation Of Developmental Process Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Negative Regulation Of Cell Differentiation Cellular Response To Growth Factor Stimulus I-SMAD Binding Response To UV Negative Regulation Of Cell Population Proliferation Ubiquitin Protein Ligase Binding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Homomeric SMAD Protein Complex Protein Kinase Activity Regulation Of Mitotic Cell Cycle Endocardial Cushion Morphogenesis Response To Light Stimulus Regulation Of ERBB Signaling Pathway Animal Organ Morphogenesis Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Cell Development Cell Junction Regulation Of Protein Metabolic Process Activin Responsive Factor Complex Developmental Growth Regulation Of Cell Communication Regulation Of Signaling Catenin Complex Kinase Activity Ruffle Membrane Activin Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Anchoring Junction Beta-catenin Binding
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