CABP2 and USP6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CABP2	USP6
Description		calcium binding protein 2	ubiquitin specific peptidase 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Plasma Membrane Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Lysosome Endosome Golgi Apparatus Plasma Membrane Membrane Recycling Endosome Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Metal Ion Binding	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Cysteine-type Deubiquitinase Activity Protein Binding Calmodulin Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Signal Transduction Visual Perception Sensory Perception Of Sound	Proteolysis Protein Deubiquitination Protein Modification Process Regulation Of Vesicle-mediated Transport Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways		Sensory processing of sound by inner hair cells of the cochlea
Drugs
Diseases
GWAS		Refractive error ( 32231278)	PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)
Interacting Genes		43 interacting genes: ADGRF5 ANKRD29 AVPI1 C22orf39 CAMK2G CARD9 CCDC33 CIMIP1 COA6 DPEP2NB EFHC2 GOLGA6L9 HOOK2 HOXD12 MXRA8 NDUFAF3 NME4 NMT1 NOP10 NUDT16L1 PPP3R1 PRR20A PRR20B PRR20C PRR20D PRR20E RD3 SNAI2 SPATC1L SPMIP6 TEKT5 THAP6 TLE5 TNNI1 TRIM35 UNKL USP6 VXN YPEL3 ZNF140 ZNF57 ZNF774 ZNF785	18 interacting genes: ANKRD11 ANKRD44 APP ATXN7L3 CABP2 CALM2 CDC42 EXOSC8 JAK1 JUN MDFI MYL2 RAB33B RAC1 RIPPLY1 TFIP11 UBC ZNF76
Entrez ID		51475	9098
HPRD ID		09535	06827
Ensembl ID		ENSG00000167791	ENSG00000129204
Uniprot IDs		F1T0K2 Q9NPB3	P35125
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium-dependent Protein Serine/threonine Phosphatase Activity Axonemal A Tubule Inner Sheath	Anatomical Structure Morphogenesis Thioesterase Binding G Protein-coupled Receptor Signaling Pathway Involved In Heart Process G Protein Activity Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Neuronal Synaptic Plasticity Growth Cone Lamellipodium Neuron Projection Organization Intracellular Signal Transduction Regulation Of Nitric Oxide Biosynthetic Process Postsynapse Regulation Of Response To Calcium Ion Regulation Of Synaptic Plasticity Macrophage Activation Intracellular Signaling Cassette Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Neuron Projection Development Regulation Of Postsynapse Organization Endocytosis Lipoprotein Particle Dendrite Development Positive Regulation Of Protein Import Microglial Cell Activation Regulation Of Nitric Oxide Metabolic Process Regulation Of MAPK Cascade Leukocyte Activation Involved In Inflammatory Response Supramolecular Fiber Organization Calcium Channel Regulator Activity Substantia Nigra Development Neural Nucleus Development Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcomere Positive Regulation Of Lamellipodium Organization Positive Regulation Of Lamellipodium Assembly Heart Process Wnt Signaling Pathway, Planar Cell Polarity Pathway GTP-dependent Protein Binding Heart Contraction Positive Regulation Of Stress Fiber Assembly Regulation Of Lamellipodium Organization Regulation Of Lamellipodium Assembly Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Phagocytosis, Engulfment Regulation Of Substrate Adhesion-dependent Cell Spreading Membrane Invagination GBD Domain Binding
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