USP6 and ANKRD44

Number of citations of the paper that reports this interaction (PMID 16555005)
2

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		USP6	ANKRD44
Gene Name		ubiquitin specific peptidase 6	ankyrin repeat domain 44
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosome Plasma Membrane Recycling Endosome
	Molecular Function	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Rab GTPase Activator Activity Protein Binding Calmodulin Binding	Protein Binding
	Biological Process	Cellular Protein Modification Process Protein Deubiquitination Positive Regulation Of Rab GTPase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Vesicle-mediated Transport Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ANKRD44 APP ATXN7L3 CDC42 EXOSC8 MDFI MYL2 RAB33B RAC1	2 interactors: USP6 WWP2
Entrez ID		9098	91526
HPRD ID		06827	14284
Ensembl ID		ENSG00000129204	ENSG00000065413
Uniprot IDs		P35125	B7Z6Z7 Q8N8A2
PDB IDs
Enriched GO Terms of Interacting Partners?		Organ Morphogenesis Anatomical Structure Morphogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Binding Regulation Of Kinase Activity Organ Development Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Lipid Kinase Activity Heart Contraction Positive Regulation Of DNA Replication Axon Guidance Negative Regulation Of Transport Regulation Of Protein Phosphorylation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway T Cell Costimulation Positive Regulation Of Cellular Protein Metabolic Process Blood Coagulation Hemostasis Regulation Of Intracellular Transport Regulation Of ERBB Signaling Pathway Negative Regulation Of Constitutive Secretory Pathway Muscle Cell Fate Specification Regulation Of Synapse Structure Or Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Kinase Activity Ephrin Receptor Signaling Pathway Cellular Localization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Axonogenesis System Development Cellular Protein Localization Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transferase Activity Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Synaptic Growth At Neuromuscular Junction Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell Projection Assembly Positive Regulation Of JNK Cascade Positive Regulation Of Cell-substrate Adhesion Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Regulation Of DNA Replication Vesicle-mediated Transport Wound Healing See more	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Regulation Of Potassium Ion Transmembrane Transporter Activity Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transport Viral Entry Into Host Cell Negative Regulation Of Transporter Activity Protein Autoubiquitination Entry Into Host Cell Proteolysis Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transport Catabolic Process Interaction With Host Protein Deubiquitination Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Modification By Small Protein Removal Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Protein Polyubiquitination Negative Regulation Of Protein Transport Viral Life Cycle Regulation Of Proteasomal Protein Catabolic Process Cellular Protein Modification Process See more
Tagcloud ?		abc aneurysmal attenuates atypical augmented autoimmunity canonical classical cyst distinguishing dysregulated ikappab ikk ikkalpha ikkbeta ikkgamma involve nemo nih3t3 overexpressed precipitates s536 translocated tre17 tumorigenic ubiquitinating uncover unexpected
Tagcloud (Difference) ?		abc aneurysmal attenuates atypical augmented autoimmunity canonical classical cyst distinguishing dysregulated ikappab ikk ikkalpha ikkbeta ikkgamma involve nemo nih3t3 overexpressed precipitates s536 translocated tre17 tumorigenic ubiquitinating uncover unexpected
Tagcloud (Intersection) ?