YKT6

Name	YKT6 vesicular SNARE protein
Structure
Novel Interactors	1 novel interactors: TCF12
Interactors	3 interactors: BET1L HSPA9 USO1
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Membrane Transport Vesicle Cytoplasmic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Neuronal Cell Body Apical Dendrite Basal Dendrite
	Molecular Function	SNAP Receptor Activity Protein Binding Transferase Activity Protein-cysteine S-palmitoyltransferase Activity Cadherin Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Membrane Fusion
Pathways	COPII-mediated vesicle transport COPI-mediated anterograde transport Intra-Golgi traffic RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
GWAS	Birth weight ( 27680694 31043758 ) Blood sugar levels ( 29403010 ) Fasting plasma glucose ( 28270201 ) Hemoglobin A1c levels ( 29403010 ) HOMA-B (corrected for HOMA-IR) ( 30369944 ) Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Offspring birth weight ( 31043758 ) Pulse pressure ( 27841878 ) Serum metabolite levels ( 31636271 ) Serum metabolite levels (CMS) ( 31636271 ) Type 2 diabetes ( 30054458 )
Entrez ID	10652
HPRD ID	16205
Ensembl ID	ENSG00000106636
Uniprot IDs	A0A7I2V4L6 A4D2J0 O15498
PDB IDs	6J74 6J7F 6J7X
GO Terms Enriched among Interactors ?	Golgi Stack Membrane Organization Golgi Vesicle Docking Membrane Fusion Regulation Of Retrograde Vesicle-mediated Transport, Golgi To ER Protein Transport Negative Regulation Of Hematopoietic Stem Cell Differentiation Cellular Localization Establishment Of Protein Localization MIB Complex Negative Regulation Of Erythrocyte Differentiation SAM Complex Calcium Import Into The Mitochondrion Establishment Of Localization In Cell Intracellular Transport HMG Box Domain Binding Response To Gonadotropin-releasing Hormone CAMP Response Element Binding Vesicle Fusion With Golgi Apparatus Negative Regulation Of Hematopoietic Progenitor Cell Differentiation TIM23 Mitochondrial Import Inner Membrane Translocase Complex Regulation Of Hematopoietic Stem Cell Differentiation Intracellular Protein Localization Mitochondrial Calcium Ion Transmembrane Transport Transcytosis Secretory Granule Localization Iron-sulfur Cluster Assembly Intracellular Protein Transport Negative Regulation Of Stem Cell Differentiation Protein Refolding BHLH Transcription Factor Binding Protein Export From Nucleus Golgi Membrane ATP-dependent Protein Folding Chaperone Inner Mitochondrial Membrane Organization SNAP Receptor Activity