NT5C3A and DPY19L1

		NT5C3A	DPY19L1
Description		5'-nucleotidase, cytosolic IIIA	dpy-19 like C-mannosyltransferase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Nuclear Body	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nucleotide Binding TRNA 2'-phosphotransferase Activity Magnesium Ion Binding Protein Binding 5'-nucleotidase Activity Transferase Activity Hydrolase Activity Metal Ion Binding	Mannosyltransferase Activity Transferase Activity Glycosyltransferase Activity
	Biological Process	Pyrimidine Nucleoside Metabolic Process Nucleotide Metabolic Process Defense Response To Virus	Protein Glycosylation
Pathways
Drugs
Diseases		Anemia due to disorders of nucleotide metabolism, including: Adenylate kinase (AK) deficiency; Uridine 5-prime monophosphate hydrolase (UMPH1) deficiency
GWAS		Estimated glomerular filtration rate ( 31152163) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red cell distribution width ( 27863252 32888494) Serum metabolite levels ( 33031748)	Fruit consumption ( 32066663) Leisure-time exercise behaviour ( 30102679) Post bronchodilator FEV1 ( 26634245) Vigorous physical activity ( 29899525)
Interacting Genes		6 interacting genes: DESI1 GNAQ NDUFAB1 UBQLN1 UBQLN2 VANGL1
Entrez ID		51251	23333
HPRD ID		05871	19410
Ensembl ID		ENSG00000122643	ENSG00000173852
Uniprot IDs		A0A090N7U2 Q9H0P0 X6RM59	A0A1B0GW05 Q2PZI1
PDB IDs		2CN1 2JGA 2VKQ
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Acyl Carrier Activity Regulation Of Proteolysis Regulation Of Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity Autophagosome Regulation Of Response To Endoplasmic Reticulum Stress Autophagosome Assembly ERAD Pathway Acyl Binding Autophagosome Organization Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Proteasomal Protein Catabolic Process Mitochondrial Large Ribosomal Subunit Binding Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Mitochondrial [2Fe-2S] Assembly Complex Protein Lipoylation Negative Regulation Of Clathrin-dependent Endocytosis Adenylate Cyclase-activating G Protein-coupled CAMP Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Vacuole Organization Protein Metabolic Process Regulation Of Macroautophagy DeSUMOylase Activity Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Phospholipase C-activating Serotonin Receptor Signaling Pathway [2Fe-2S] Cluster Assembly Mannosyltransferase Activity Importin-alpha Family Protein Binding Palmitoyl-(protein) Hydrolase Activity Protein Desumoylation Response To Endoplasmic Reticulum Stress Mucociliary Clearance Iron-sulfur Cluster Assembly Complex Macromolecule Depalmitoylation Regulation Of Toll-like Receptor 3 Signaling Pathway Phototransduction, Visible Light Long-chain Fatty Acyl-CoA Hydrolase Activity Aggrephagy Autophagy G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Receptor Internalization Guanyl Nucleotide Binding Regulation Of Clathrin-dependent Endocytosis	TRNA 2'-phosphotransferase Activity Pyrimidine Nucleoside Metabolic Process 5'-nucleotidase Activity
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