MTRES1 and TUBE1

Data Source: HiPPIP (Novel)

		MTRES1	TUBE1
Name		mitochondrial transcription rescue factor 1	tubulin epsilon 1
Structure			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Pericentriolar Material Cytoplasm Centrosome Cytoskeleton Microtubule Microtubule Cytoskeleton
	Molecular Function	TRNA Binding RNA Binding Protein Binding Ribosomal Large Subunit Binding	Nucleotide Binding Structural Constituent Of Cytoskeleton GTP Binding
	Biological Process	Rescue Of Stalled Ribosome Regulation Of Mitochondrial Transcription	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Centrosome Cycle
Pathways		Mitochondrial ribosome-associated quality control	None
Drugs		None	Vinblastine
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		1 novel interactors: TUBE1	6 novel interactors: CDC40 DPAGT1 GOPC MTRES1 NUDC RPS20
Interacting Genes		4 interacting genes: APP CFTR COPS5 STRAP	None recorded
Entrez ID		51250	51175
HPRD ID		12873	06298
Ensembl ID		ENSG00000130349	ENSG00000074935
Uniprot IDs		A0A0D9SEI0 Q9P0P8	Q9UJT0
PDB IDs		7A5H	Not available
GO Terms Enriched among Interactors		Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of JNK Cascade Enzyme Binding Regulation Of Response To Calcium Ion Recycling Endosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Macrophage Migration Inhibitory Factor Binding U2 SnRNP Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Exosomal Secretion Intermediate-density Lipoprotein Particle Developmental Maturation Early Endosome Membrane Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Transepithelial Water Transport Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity Negative Regulation Of Anion Channel Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity