TUBE1 and MTRES1

Data Source: HiPPIP (Novel)

		TUBE1	MTRES1
Name		tubulin epsilon 1	mitochondrial transcription rescue factor 1
Structure		No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Cytoskeleton Microtubule Microtubule Cytoskeleton	Mitochondrion Mitochondrial Matrix
	Molecular Function	Nucleotide Binding Structural Constituent Of Cytoskeleton GTP Binding	TRNA Binding RNA Binding Protein Binding Ribosomal Large Subunit Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Centrosome Cycle	Rescue Of Stalled Ribosome Regulation Of Mitochondrial Transcription
Pathways		None	Mitochondrial ribosome-associated quality control
Drugs		Vinblastine	None
GWAS		No GWAS studies recorded	No GWAS studies recorded
Novel Interactors		6 novel interactors: CDC40 DPAGT1 GOPC MTRES1 NUDC RPS20	1 novel interactors: TUBE1
Interacting Genes		None recorded	4 interacting genes: APP CFTR COPS5 STRAP
Entrez ID		51175	51250
HPRD ID		06298	12873
Ensembl ID		ENSG00000074935	ENSG00000130349
Uniprot IDs		Q9UJT0	A0A0D9SEI0 Q9P0P8
PDB IDs		Not available	7A5H
GO Terms Enriched among Interactors		UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity Negative Regulation Of Anion Channel Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity	Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of JNK Cascade Enzyme Binding Regulation Of Response To Calcium Ion Recycling Endosome Amylin Binding Endosome To Plasma Membrane Transport Vesicle Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Cellular Response To CAMP Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Macrophage Migration Inhibitory Factor Binding U2 SnRNP Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization Exosomal Secretion Intermediate-density Lipoprotein Particle Developmental Maturation Early Endosome Membrane Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Transepithelial Water Transport Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway