ASB3 and CRACR2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ASB3	CRACR2A
Description		ankyrin repeat and SOCS box containing 3	calcium release activated channel regulator 2A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Neutrophil degranulation
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Bronchodilator response in asthma ( 25562107) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime nap ( 33568662) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Excessive daytime sleepiness ( 27992416) Femur bone mineral density x serum urate levels interaction ( 34046847) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Hematocrit ( 32888494) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Interleukin-1-receptor antagonist levels ( 22205395) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Red cell distribution width ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systemising ( 31508503) Type 2 diabetes ( 26818947)	Femur bone mineral density x serum urate levels interaction ( 34046847) Severe insulin-deficient type 2 diabetes ( 34737425)
Interacting Genes		12 interacting genes: CRACR2A DSCR9 ENKD1 KDM1A PRMT6 RIN3 RIPK4 TEPSIN TLE5 TNS2 UBC ZAP70	35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655
Entrez ID		51130	84766
HPRD ID		05769	10079
Ensembl ID		ENSG00000115239	ENSG00000130038
Uniprot IDs		Q9Y575	Q9BSW2
PDB IDs			6PSD
Enriched GO Terms of Interacting Partners?			Identical Protein Binding
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