THAP4 and BSND

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		THAP4	BSND
Description		THAP domain containing 4	barttin CLCNK type accessory subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Plasma Membrane Membrane Basolateral Plasma Membrane Protein-containing Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Isomerase Activity Heme Binding Identical Protein Binding Metal Ion Binding Peroxynitrite Isomerase Activity Nitric Oxide Binding	Chloride Channel Activity Protein Binding Chloride Channel Regulator Activity
	Biological Process	Tyrosine Metabolic Process Nitrate Metabolic Process	Chloride Transport Sensory Perception Of Sound Chloride Transmembrane Transport
Pathways			Stimuli-sensing channels
Drugs
Diseases			Bartter syndrome
GWAS		Brain structure ( 20171287) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 34021172) Platelet count ( 32888494) Prostate cancer ( 23535732) Thyroid stimulating hormone levels ( 32769997)	Allergic rhinitis ( 25085501) Carotid intima media thickness x smoking interaction ( 32117412) Coronary artery disease ( 32469254 33020668) Medication use (HMG CoA reductase inhibitors) ( 31015401) Mitochondrial DNA copy number ( 30704525)
Interacting Genes		43 interacting genes: AGTRAP AIG1 AMD1 ANKRD46 APP BSND CACNG1 CD81 CLCA4 CMTM5 CMTM7 COL4A5 CPNE2 CTSA CYP4F2 DGAT2L6 FKBP7 GIMAP1 GPR37L1 IGFBP5 LAT LCOR LPAR3 MAL2 MAPK6 MOB4 MS4A1 NDRG4 PLP2 RMDN2 RTP2 SCAMP1 SLC30A8 SYP TMEM107 TMEM60 TMEM86A TMEM86B TNFRSF10D TPD52 TRIM54 TTPA YIPF6	28 interacting genes: ADIPOQ APOL2 APP ARFIP1 BMP10 CDIPT CERT1 COL4A5 COL8A2 CSGALNACT2 CTSA ECPAS FATE1 GAD2 IGFBP5 JAGN1 MYG1 PBX3 PLSCR2 PTPN9 SLC30A8 SPG21 STX8 TBRG4 THAP4 TMEM60 VAMP3 ZFPL1
Entrez ID		51078	7809
HPRD ID		11630	05914
Ensembl ID		ENSG00000176946	ENSG00000162399
Uniprot IDs		Q8WY91	Q5VU50 Q8WZ55
PDB IDs		3IA8
Enriched GO Terms of Interacting Partners?		Membrane Alkenylglycerophosphocholine Hydrolase Activity Vitamin E Metabolic Process	Amyloid-beta Complex Lipoprotein Metabolic Process Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting Regulation Of Response To Calcium Ion Regulation Of Establishment Of Protein Localization Recycling Endosome Trans-Golgi Network Membrane Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Response To Cytokine Regulation Of Protein Localization Regulation Of Protein Transport Endoplasmic Reticulum Locomotory Behavior Response To CAMP Golgi Apparatus Endoplasmic Reticulum Lumen Positive Regulation Of CAMP/PKA Signal Transduction Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen Trimer Extracellular Matrix Structural Constituent Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy Posterior Compartment Specification Anterior Compartment Pattern Formation Regulation Of Cellular Localization Mitochondrial MRNA Processing Regulation Of Hormone Secretion Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Response To Glucose Positive Regulation Of Glycogen (starch) Synthase Activity Response To Monosaccharide Phosphatidylinositol-4-phosphate Binding Amide Transport Intermembrane Sphingolipid Transfer CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Negative Regulation Of Retrograde Transport, Endosome To Golgi Peroxynitrite Isomerase Activity Insulin Metabolic Process Early Endosome Negative Regulation Of Secretion By Cell Regulation Of System Process
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