ZNF691 and TRIM41

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF691	TRIM41
Description		zinc finger protein 691	tripartite motif containing 41
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Protein Monoubiquitination Positive Regulation Of Signal Transduction Protein Ubiquitination Innate Immune Response Defense Response To Virus Positive Regulation Of Type I Interferon-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide
Pathways		Generic Transcription Pathway	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Liver enzyme levels (alkaline phosphatase) ( 33972514) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: AKT1 HAP1 PICK1 TRIM41	144 interacting genes: AEN AKTIP ANKRD23 AP1M1 APP AQP1 BIVM BRAP BYSL C8orf33 CARD10 CCNL2 CEP44 CHD2 CSNK2A1 CSNK2A2 DDX41 DEPTOR DRC4 DVL3 EHHADH EZHIP FAM124A FAM161A FAM9A FLACC1 FRA10AC1 GPATCH2L IKBKG JRK KATNBL1 KIFC3 KRTAP10-8 KRTAP10-9 MAGEH1 MCRS1 MEOX1 MEOX2 MFAP1 MID2 MOBP MORF4L1 MORF4L2 MPP3 NCK2 NEDD4L NFE2L2 NOD2 PBX4 PHC2 PHF11 PHF7 PLAGL2 PRDM14 PRKCA PRKCB PRPF31 PTPN3 PUS7L RBAK RNPS1 SORBS3 SRPK2 STX11 SUV39H1 SYCE1 SYTL4 TBC1D26 TCEA2 TCEANC TLE5 TNNI1 TOP3B TP53 TRAIP TRIM17 TRIM26 TRIM4 TRIM52 TRIM55 TRIM63 UBE2D1 UBE2D2 UBE2I ZBTB24 ZBTB26 ZBTB38 ZBTB39 ZBTB48 ZBTB8A ZCCHC7 ZFP1 ZFP2 ZFP64 ZMAT5 ZNF121 ZNF134 ZNF138 ZNF165 ZNF2 ZNF219 ZNF24 ZNF250 ZNF251 ZNF26 ZNF263 ZNF264 ZNF266 ZNF275 ZNF286A ZNF319 ZNF329 ZNF343 ZNF398 ZNF408 ZNF417 ZNF439 ZNF460 ZNF473 ZNF48 ZNF490 ZNF497 ZNF526 ZNF552 ZNF564 ZNF575 ZNF587 ZNF629 ZNF648 ZNF653 ZNF655 ZNF670 ZNF691 ZNF696 ZNF71 ZNF773 ZNF780A ZNF784 ZNF792 ZNF835 ZNF837 ZSCAN16 ZSCAN21 ZSCAN26
Entrez ID		51058	90933
HPRD ID		14229	15558
Ensembl ID		ENSG00000164011	ENSG00000146063
Uniprot IDs		Q5VV50 Q5VV52	Q8WV44
PDB IDs			2EGM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Cilium Assembly Positive Regulation Of Cellular Component Organization Response To Rapamycin Positive Regulation Of Protein Localization To Endoplasmic Reticulum Cellular Response To Oxygen Levels Nitric-oxide Synthase Regulator Activity Establishment Of Protein Localization Positive Regulation Of Organelle Assembly Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Negative Regulation Of SREBP Signaling Pathway Response To Insulin-like Growth Factor Stimulus Negative Regulation Of Fatty Acid Beta-oxidation Intracellular Transport Positive Regulation Of TORC2 Signaling Cellular Response To Decreased Oxygen Levels TRNA Stabilization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Hydrogen Peroxide Potassium Channel Activator Activity Mammalian Oogenesis Stage RNA (guanine-N7)-methylation Positive Regulation Of Innate Immune Response Negative Regulation Of Fatty Acid Transport Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Cellular Response To Peptide Positive Regulation Of Cilium Assembly Regulation Of Organelle Assembly Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Cell Projection Assembly Maintenance Of Protein Location In Mitochondrion TRNA (guanine-N7)-methylation Activation-induced Cell Death Of T Cells Regulation Of Long-chain Fatty Acid Import Into Cell TORC2 Complex Binding Cellular Response To Nutrient Levels Cellular Response To Rapamycin Regulation Of Organelle Organization Regulation Of Vesicle-mediated Transport Peripheral Nervous System Myelin Maintenance Cellular Response To Starvation Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Deoxyribonuclease Activity Regulation Of Cell Communication Positive Regulation Of Transport Protein Transport Negative Regulation Of Protein Localization To Lysosome Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Response To Starvation	Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Nucleus RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Protein Ligase Activity Negative Regulation Of DNA-templated Transcription Histone H3T6 Kinase Activity Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process Sequence-specific Double-stranded DNA Binding Protein Kinase CK2 Complex Protein Ubiquitination Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Protein Modification By Small Protein Conjugation Positive Regulation Of Transcription By RNA Polymerase II Protein Kinase C Signaling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Hematopoietic Stem Cell Differentiation Somite Specification
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