CELA2B and KRTAP3-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CELA2B	KRTAP3-1
Description		chymotrypsin like elastase 2B	keratin associated protein 3-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Structural Molecule Activity Protein Binding
	Biological Process	Proteolysis
Pathways			Keratinization
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 29273807) Body size at age 10 ( 32376654) Estimated glomerular filtration rate ( 31015462) Hemoglobin ( 32888494) Resistant hypertension ( 30237584)
Interacting Genes		4 interacting genes: CALCOCO2 KRT40 KRTAP3-1 ZDHHC15	83 interacting genes: ADAM12 AGXT ANAPC11 BMP7 CDKN1A CELA2B CERK CFP CIMIP1 CNNM3 CREB5 CTRC CYSRT1 DMRT3 DOCK2 FAM168A FAM222B FOXH1 FRS3 GATA2 GNE GPS2 GSTP1 HCK HEY2 HOXB9 HR HSF4 IL16 ITGB4 KRTAP10-8 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP6-1 KRTAP9-3 KRTAP9-8 LCE1B LCE2B LCE3A LCE3D LCE4A LCE5A LMO4 LRRC41 MAPKBP1 MRPL40 MYPOP NOTCH2NLA NTAQ1 OTX1 PATZ1 PCSK5 PHLDA1 PKIB PLSCR4 POLR1C PTPMT1 PVR RBPMS RECK REEP6 RNF44 SAMD7 SAXO4 SLC5A5 SMARCC1 SPAG8 SPMIP9 TEKT3 TLX3 TNS2 VASN VENTX VGLL3 WDR25 YPEL3 ZFHX2 ZNF414 ZNF446
Entrez ID		51032	83896
HPRD ID		06496	13937
Ensembl ID		ENSG00000215704	ENSG00000212901
Uniprot IDs		P08218 Q6ISP9	Q9BYR8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Myofibroblast Contraction Folic Acid Transmembrane Transporter Activity Leading Edge Of Lamellipodium Lymphatic Endothelial Cell Fate Commitment Water Transmembrane Transporter Activity Keratin Filament Structural Molecule Activity Intermediate Filament Protein-cysteine S-myristoyltransferase Activity Protein Targeting To Golgi Apparatus Xenophagy Positive Regulation Of Autophagosome Maturation Chemokine Binding Protein-cysteine S-stearoyltransferase Activity Folic Acid Transport Synaptic Vesicle Maturation Positive Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Platelet Aggregation Regulation Of Lamellipodium Morphogenesis Tetraspanin-enriched Microdomain Epithelial Cell Fate Commitment Peptidyl-L-cysteine S-palmitoylation Positive Regulation Of Cellular Component Organization Regulation Of Autophagosome Maturation Lymphangiogenesis Water Channel Activity Positive Regulation Of Dendrite Development Positive Regulation Of Homotypic Cell-cell Adhesion Lymph Node Development Filopodium Membrane Protein Palmitoylation Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Intermediate Filament Protein Binding Keratinization Keratin Filament Epidermis Development Axonemal A Tubule Inner Sheath Tissue Development Ventral Spinal Cord Interneuron Differentiation Heart Trabecula Morphogenesis Cellular Response To Cell-matrix Adhesion
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