SLC45A1 and SLC2A5

		SLC45A1	SLC2A5
Description		solute carrier family 45 member 1	solute carrier family 2 member 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Plasma Membrane Membrane Apical Plasma Membrane Specific Granule Membrane Sarcolemma Extracellular Exosome
	Molecular Function	D-glucose:proton Symporter Activity Sucrose:proton Symporter Activity Symporter Activity Galactose:proton Symporter Activity Transmembrane Transporter Activity	Fructose Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity Fructose Binding
	Biological Process	Galactose Transmembrane Transport Sucrose Transport Transmembrane Transport D-glucose Transmembrane Transport	Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Carbohydrate Metabolic Process Response To Fructose Fructose Transmembrane Transport D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport Cellular Response To Fructose Stimulus Intestinal Hexose Absorption D-glucose Transmembrane Transport Fructose Import Across Plasma Membrane
Pathways			Neutrophil degranulation Intestinal hexose absorption
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 23468962) Brown vs. black hair color ( 30531825) Depression ( 29700475) Fish- and plant-related diet ( 32066663) Hair color ( 29662168) Hair shape ( 29220522) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hippocampal volume in normal cognition ( 29274321) Inflammatory skin disease ( 25574825) Morning person ( 30696823) Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311) Psoriasis ( 25903422 23143594) Schizophrenia ( 29483656 28991256) Strep throat ( 28928442) Subclinical trait of interstitial lung disease (basilar peel-core ratio of high attentuation areas on CT scan) ( 28521775) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		1 interacting genes: PPP1CA	15 interacting genes: ARL13B ATP6V0B CCL5 COMT EVI2B FCRL3 LMNA MGST3 MTERF3 PAGE1 RPSA SCN3B TMEM130 TMEM237 USP40
Entrez ID		50651	6518
HPRD ID		19078	00690
Ensembl ID		ENSG00000162426	ENSG00000142583
Uniprot IDs		Q9Y2W3	A0A140VJK5 B4DG19 B4DT82 P22732
PDB IDs
Enriched GO Terms of Interacting Partners?		Cardiac Muscle Tissue Development Positive Regulation Of Pentose-phosphate Shunt Positive Regulation Of Cytoplasmic Translational Initiation Cellular Response To Oxygen Levels Energy Reserve Metabolic Process Regulation Of Growth Regulation Of Circadian Rhythm TORC1 Complex Generation Of Precursor Metabolites And Energy Regulation Of Membrane Permeability Inositol Hexakisphosphate Binding Response To Temperature Stimulus RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding Cellular Response To Decreased Oxygen Levels Regulation Of Locomotor Rhythm Nucleobase-containing Small Molecule Metabolic Process Regulation Of Carbohydrate Catabolic Process Calcium-mediated Signaling Cellular Response To Hypoxia Energy Derivation By Oxidation Of Organic Compounds Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade TFIIIC-class Transcription Factor Complex Binding Regulation Of Pentose-phosphate Shunt RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding Positive Regulation Of Cell Growth Striated Muscle Tissue Development Negative Regulation Of TORC2 Signaling Cellular Response To Insulin Stimulus Muscle Tissue Development Regulation Of Stress Fiber Assembly Positive Regulation Of Small Molecule Metabolic Process Regulation Of Calcium-mediated Signaling Cellular Response To Methionine Voluntary Musculoskeletal Movement 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Response To Insulin Small Molecule Metabolic Process Negative Regulation Of Lysosome Organization Regulation Of Translational Initiation Regulation Of Cell Growth T-helper 1 Cell Lineage Commitment RNA Polymerase III Type 3 Promoter Sequence-specific DNA Binding Positive Regulation Of Wound Healing, Spreading Of Epidermal Cells Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of SCF-dependent Proteasomal Ubiquitin-dependent Catabolic Process Purine Ribonucleotide Biosynthetic Process Hormone Receptor Binding Ribose Phosphate Biosynthetic Process Regulation Of Blood Pressure
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