SYCP3 and C14orf119

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYCP3	C14orf119
Description		synaptonemal complex protein 3	chromosome 14 open reading frame 119
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Synaptonemal Complex Lateral Element Nucleus Chromosome	Mitochondrion Cytosol
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	Male Meiosis I Spermatid Development Sperm DNA Condensation Cell Division Meiotic Cell Cycle
Pathways		Meiotic synapsis
Drugs
Diseases		Azoospermia, including: Azoospermia; Azoospermia due to perturbations of meiosis
GWAS		Brain morphology (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: C14orf119 CDC37 LIG4 NXF1 PABPC1 SYCP2	56 interacting genes: ACTN4 ARID3C ARID5A AUNIP BEND7 BIN3 C1QTNF1 CCND3 CDC14A CHMP1A CLPP CTAG1A CTAG1B DDIT4L DECR2 DYNLL1 DYNLL2 HES6 HLX HMG20B ITGB3BP KHDC4 KRT4 KRT78 KRTAP13-3 LASP1 LDB2 LENG1 LRRCC1 MEOX1 MORN3 MYF5 NIF3L1 NME4 NRIP3 NUP54 NUP62 PBX4 PHACTR1 PINX1 RAB3IL1 REL RHOU RND3 RNF4 RPIA SMCP SNX8 SSX4 SSX4B STN1 SYCP3 TEX35 TLE5 UBXN11 WASHC1
Entrez ID		50511	55017
HPRD ID		07265	16595
Ensembl ID		ENSG00000139351	ENSG00000179933
Uniprot IDs		Q8IZU3	Q9NWQ9
PDB IDs		4CPC
Enriched GO Terms of Interacting Partners?		Establishment Of Integrated Proviral Latency DNA Ligase (ATP) Activity DNA Ligase IV Complex Pro-B Cell Differentiation T Cell Receptor V(D)J Recombination Establishment Of Viral Latency DNA Ligase Activity DN2 Thymocyte Differentiation Fertilization Lymphatic Endothelial Cell Fate Commitment Radial Pattern Formation Male Genitalia Morphogenesis Cytoplasmic Stress Granule HSP90-CDC37 Chaperone Complex Double-strand Break Repair Via Classical Nonhomologous End Joining Lymphoid Progenitor Cell Differentiation Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development DNA-dependent Protein Kinase-DNA Ligase 4 Complex Single Strand Break Repair Immunoglobulin V(D)J Recombination AMP Binding Chordate Embryonic Development Nonhomologous End Joining Complex Nucleotide-excision Repair, DNA Gap Filling In Utero Embryonic Development Lymph Vessel Development Maternal Placenta Development Trophoblast Giant Cell Differentiation Epithelial Cell Fate Commitment Genitalia Morphogenesis Lateral Element Nuclear RNA Export Factor Complex Nuclear Inclusion Body MRNA Binding Transcription Export Complex Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Positive Regulation Of Type 2 Mitophagy Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Translation Activator Activity MCRD-mediated MRNA Stability Complex Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay CRD-mediated MRNA Stabilization Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Cellular Response To Lithium Ion Interneuron Migration Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway	Protein Binding
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