ATP5A1 and ATPAF1

Number of citations of the paper that reports this interaction (PMID 11410595)
12

Data Source:
BioGRID (two hybrid)

		ATP5A1	ATPAF1
Gene Name		ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	ATP synthase mitochondrial F1 complex assembly factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Plasma Membrane COP9 Signalosome Membrane Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Extracellular Vesicular Exosome	Mitochondrion
	Molecular Function	Protein Binding ATP Binding ATPase Activity Transmembrane Transporter Activity MHC Class I Protein Binding Poly(A) RNA Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process ATP Biosynthetic Process Embryo Development ATP Hydrolysis Coupled Proton Transport Respiratory Electron Transport Chain Mitochondrial ATP Synthesis Coupled Proton Transport Cellular Metabolic Process Small Molecule Metabolic Process	Protein Complex Assembly
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Mitochondrial protein import The citric acid (TCA) cycle and respiratory electron transport Formation of ATP by chemiosmotic coupling
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AIMP1 APP ATP5B ATP5C1 ATPAF1 ATPAF2 CSNK2A1 RPS6KB2 SHBG YWHAB YWHAG YWHAQ YWHAZ	2 interactors: ATP5A1 ATP5B
Entrez ID		498	64756
HPRD ID		01258	12332
Ensembl ID		ENSG00000152234	ENSG00000123472
Uniprot IDs		B4DY56 K7ENP3 P25705	A8MRA7 I3L448 Q5TC12
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Apoptotic Process Programmed Cell Death Cell Death Death Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Intracellular Transport Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Establishment Of Localization In Cell Mitochondrial ATP Synthesis Coupled Proton Transport Positive Regulation Of Organelle Organization Protein Targeting Mitochondrial Transport Regulation Of Intracellular Transport Regulation Of Organelle Organization Cellular Localization ATP Synthesis Coupled Proton Transport ATP Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Phosphorylation Chemotaxis Positive Regulation Of Cell Death Phosphate-containing Compound Metabolic Process Locomotion Positive Regulation Of Signal Transduction Regulation Of Establishment Of Protein Localization Defense Response Positive Regulation Of Transport Primary Spermatocyte Growth Regulation Of Protein Localization Regulation Of Apoptotic Process Purine Ribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Cellular Protein Metabolic Process Movement Of Cell Or Subcellular Component Membrane Organization Regulation Of Cell Death Developmental Cell Growth Nucleoside Triphosphate Biosynthetic Process Negative Regulation Of Protein Metabolic Process Axon Guidance Intracellular Protein Transport Synaptic Growth At Neuromuscular Junction Ribonucleoside Monophosphate Biosynthetic Process	Mitochondrial ATP Synthesis Coupled Proton Transport ATP Synthesis Coupled Proton Transport ATP Biosynthetic Process ATP Hydrolysis Coupled Proton Transport Purine Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Triphosphate Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Respiratory Electron Transport Chain Electron Transport Chain ATP Metabolic Process Mitochondrial Transport Cellular Respiration Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Hydrogen Ion Transmembrane Transport Proton Transport Purine Nucleoside Metabolic Process Ribonucleotide Metabolic Process Nucleoside Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Generation Of Precursor Metabolites And Energy Nucleotide Metabolic Process Negative Regulation Of Cell Adhesion Involved In Substrate-bound Cell Migration Nucleobase-containing Small Molecule Metabolic Process Monovalent Inorganic Cation Transport Cation Transmembrane Transport Organophosphate Metabolic Process Cation Transport Negative Regulation Of Endothelial Cell Proliferation Lipid Metabolic Process Substrate-dependent Cell Migration Ion Transmembrane Transport Regulation Of Intracellular PH Regulation Of Cellular PH Oxidation-reduction Process Intracellular Transport Transmembrane Transport Ion Transport Regulation Of PH Regulation Of Endothelial Cell Proliferation Establishment Of Localization In Cell Small Molecule Metabolic Process Cellular Localization Negative Regulation Of Epithelial Cell Proliferation Osteoblast Differentiation Phosphate-containing Compound Metabolic Process
Tagcloud ?		2de angustifolia apoa1 bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically prdx2 predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Difference) ?		2de angustifolia apoa1 bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically prdx2 predictedinteractions scrutinized searching slowing snca string sum tof
Tagcloud (Intersection) ?