NRL and FIZ1

Number of citations of the paper that reports this interaction (PubMedID 12566383)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		NRL	FIZ1
Description		neural retina leucine zipper	FLT3 interacting zinc finger 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Leucine Zipper Domain Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding	Transcription Coactivator Activity Zinc Ion Binding Receptor Tyrosine Kinase Binding Metal Ion Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Retinal Rod Cell Development	Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Attention deficit hyperactivity disorder symptom score ( 27663945) Liver fibrosis and steatohepatitis severity (MRI cT1 measure) ( 32247823) Post bronchodilator FEV1/FVC ratio ( 26634245)	Periodontitis (Mean PAL) ( 24024966) Triglyceride levels ( 32203549)
Interacting Genes		7 interacting genes: CRX EDF1 FIZ1 MAPK1 MAPK14 NR2E3 UBR5	4 interacting genes: FLT3 KLHL20 NRL OGT
Entrez ID		4901	84922
HPRD ID		08875	07870
Ensembl ID		ENSG00000129535	ENSG00000179943
Uniprot IDs		P54845	Q96SL8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process MAP Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Protein Import Into Nucleus Regulation Of Intracellular Transport Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Retina Development In Camera-type Eye Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Protein Transport Cellular Response To Tumor Necrosis Factor Positive Regulation Of Protein Localization To Nucleus Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cytosine Metabolic Process Nuclear Receptor-mediated Signaling Pathway Heterochromatin Boundary Formation Regulation Of Cellular Localization Nucleus Regulation Of Transcription By RNA Polymerase II Regulation Of Ossification Regulation Of Nucleocytoplasmic Transport Response To Tumor Necrosis Factor Ficolin-1-rich Granule Lumen Regulation Of Synaptic Membrane Adhesion Interleukin-34-mediated Signaling Pathway Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Hormone-mediated Signaling Pathway Regulation Of Golgi Inheritance Cytoplasm Protein Quality Control	Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Type II Interferon Binding Vascular Endothelial Growth Factor Receptor Activity Common Myeloid Progenitor Cell Proliferation Cell Development Pro-B Cell Differentiation Myeloid Progenitor Cell Differentiation Phosphatidylinositol 3-kinase Activator Activity Hemopoiesis Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Protein K33-linked Ubiquitination Retinal Rod Cell Development Regulation Of Transcription By Glucose Regulation Of Programmed Cell Death Leucine Zipper Domain Binding NSL Complex Lymphoid Progenitor Cell Differentiation
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