RPL10A and SRPR

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPL10A	SRPR
Gene Name		ribosomal protein L10a	signal recognition particle receptor (docking protein)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Extracellular Vesicular Exosome	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding	GTPase Activity Signal Recognition Particle Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Anatomical Structure Morphogenesis Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Gene Expression Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	IRE1alpha activates chaperones Translation SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ACTB RGS17 SGOL1 SRPR YWHAQ	3 interactors: RPL10A RUSC2 SSR2
Entrez ID		4736	6734
HPRD ID		10199	01645
Ensembl ID		ENSG00000198755	ENSG00000182934
Uniprot IDs		P62906	P08240
PDB IDs		3J3B	2FH5 2GO5
Enriched GO Terms of Interacting Partners?		Substantia Nigra Development Neural Nucleus Development Midbrain Development Membrane Organization	SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Protein Localization To Organelle Translation Cytoplasmic Transport Membrane Organization Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Viral Transcription Intracellular Transport Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Tagcloud ?		advantage biotin bira combinatorial complexity complicate crucially danio dissecting enrichment equipment inherently interesting intersecting manipulations metazoan organism polysome relies rely rerio starting subpopulations suspension suspensions tagged take theme zebrafish	ap2b2 ap3d1and cho correlating ddb1 dhfr displaying division doubling exposing extrinsic hamster intrinsic landscape mthfd2 ovary pca polarity principal productivity proteomics ranked rcan1 shotgun technologies tmem20 top traits transcriptomics
Tagcloud (Difference) ?		advantage biotin bira combinatorial complexity complicate crucially danio dissecting enrichment equipment inherently interesting intersecting manipulations metazoan organism polysome relies rely rerio starting subpopulations suspension suspensions tagged take theme zebrafish	ap2b2 ap3d1and cho correlating ddb1 dhfr displaying division doubling exposing extrinsic hamster intrinsic landscape mthfd2 ovary pca polarity principal productivity proteomics ranked rcan1 shotgun technologies tmem20 top traits transcriptomics
Tagcloud (Intersection) ?