RPL10A and SRPRA

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		RPL10A	SRPRA
Description		ribosomal protein L10a	SRP receptor subunit alpha
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribosome Focal Adhesion Postsynaptic Density Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Extracellular Exosome Ribonucleoprotein Complex	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Extracellular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	Nucleotide Binding RNA Binding GTPase Activity Signal Recognition Particle Binding Protein Binding GTP Binding
	Biological Process	Cytoplasmic Translation Translation Response To Ethanol	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Intracellular Protein Transport Protein Targeting To ER
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: ACTB DUX4 OGT PTEN RGS17 SGO1 SRPRA YWHAQ	3 interacting genes: RPL10A RUSC2 SSR2
Entrez ID		4736	6734
HPRD ID		10199	01645
Ensembl ID		ENSG00000198755	ENSG00000182934
Uniprot IDs		P62906	P08240
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6LQM 6LSR 6LU8 6OLG 6QZP 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FL2 8FL3 8FL4 8G5Y 8G60 8G61 8G6J 8IDY 8IFD 8IFE 8INF 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFC 8UKB 8XSX 8XSY 8Y0W 8YOP	2FH5 2GO5 5L3Q 6Y32 7NFX
Enriched GO Terms of Interacting Partners?		Synapse Positive Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Population Maintenance Regulation Of G0 To G1 Transition Substantia Nigra Development Neural Nucleus Development Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Negative Regulation Of Synaptic Vesicle Clustering Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Norepinephrine Uptake Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Structural Constituent Of Postsynaptic Actin Cytoskeleton Regulation Of Protein Localization To Cell Periphery Regulation Of Transepithelial Transport Axonogenesis Regulation Of Protein Localization To Membrane Protein Localization To Adherens Junction Dense Body Regulation Of Cell Cycle G1/S Phase Transition Transporter Regulator Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Morphogenesis Of A Polarized Epithelium Kinetochore Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Circadian Rhythm Rhythmic Synaptic Transmission Postsynaptic Density Assembly Signal Recognition Particle Receptor Complex SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Mitotic Sister Chromatid Cohesion, Centromeric Negative Regulation Of G0 To G1 Transition BBAF Complex
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