SRPRA and SSR2

Number of citations of the paper that reports this interaction (PubMedID 3021779)
30

Data Source:
HPRD (in vitro, in vivo)

		SRPRA	SSR2
Description		SRP receptor subunit alpha	signal sequence receptor subunit 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Nucleotide Binding RNA Binding GTPase Activity Signal Recognition Particle Binding Protein Binding GTP Binding	Protein Binding
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Intracellular Protein Transport Protein Targeting To ER	In Utero Embryonic Development Cotranslational Protein Targeting To Membrane
Pathways		SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes	SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS			Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		3 interacting genes: RPL10A RUSC2 SSR2	1 interacting genes: SRPRA
Entrez ID		6734	6746
HPRD ID		01645	02923
Ensembl ID		ENSG00000182934	ENSG00000163479
Uniprot IDs		P08240	P43308
PDB IDs		2FH5 2GO5 5L3Q 6Y32 7NFX	8B6L
Enriched GO Terms of Interacting Partners?			Signal Recognition Particle Binding SRP-dependent Cotranslational Protein Targeting To Membrane Signal Recognition Particle Receptor Complex SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Protein Targeting Establishment Of Protein Localization To Membrane
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