NDUFV2 and SP110

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NDUFV2	SP110
Gene Name		NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	SP110 nuclear body protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Plasma Membrane Respiratory Chain Complex I	Nucleus Nucleolus
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity Electron Carrier Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding	DNA Binding Chromatin Binding Signal Transducer Activity Zinc Ion Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Nervous System Development Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process Cardiac Muscle Tissue Development	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated Signal Transduction Viral Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs		NADH
Diseases
GWAS			Chronic lymphocytic leukemia ( 18758461) Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: CRMP1 KAT5 SP110	11 interactors: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9
Entrez ID		4729	3431
HPRD ID		02757	06832
Ensembl ID		ENSG00000178127	ENSG00000135899
Uniprot IDs		P19404	G5E9C0 Q9HB58
PDB IDs
Enriched GO Terms of Interacting Partners?		Pyrimidine Nucleobase Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Viral Process DNA Damage Response, Signal Transduction Resulting In Transcription Chromatin Modification Cellular Response To Estradiol Stimulus Negative Regulation Of Interleukin-2 Production Chromatin Organization Positive Regulation Of Protein Acetylation Cellular Response To Estrogen Stimulus	Nucleoside Metabolic Process Fetal Process Involved In Parturition Positive Regulation Of Histone H3-K14 Acetylation Threonylcarbamoyladenosine Biosynthetic Process Skeletal Muscle Cell Proliferation Cellular Metabolic Process Regulation Of Histone H3-K14 Acetylation Nucleobase-containing Compound Metabolic Process Digestive Tract Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Maturation Digestive System Development Positive Regulation Of Programmed Cell Death Threonylcarbamoyladenosine Metabolic Process Thyroid Hormone Transport Intestinal Epithelial Cell Maturation Anatomical Structure Development Response To Glucocorticoid Positive Regulation Of Cell Death Response To Corticosteroid Cellular Nitrogen Compound Metabolic Process Response To Cortisol Thymidine Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Response To Toxic Substance Regulation Of Stem Cell Division Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Developmental Process Nitrogen Compound Metabolic Process
Tagcloud ?		accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn impa2 metabotropic ncam1 nd4 nos1 nos1ap nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah	cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole
Tagcloud (Difference) ?		accomplices counterbalance dao daoa dictate dpysl2 dtnbp1 famine grin1 grin2b grm3 grm4 hypomyelination il1b il1rn impa2 metabotropic ncam1 nd4 nos1 nos1ap nurture oligodendrocyte pdlim5 pik3c3 pip5k2a reconcile rgs4 ywhah	cavitary cc classification ct dimensionality employed except explore fresh gc genotype heterozygous homozygous instead mtb multifactor mybbp1a mycobacterium pathological progress promising ptb rela rs3809849 rs9061 rs9905742 tree tuberculosis whole
Tagcloud (Intersection) ?