NDUFB9 and PSMB9

		NDUFB9	PSMB9
Description		NADH:ubiquinone oxidoreductase subunit B9	proteasome 20S subunit beta 9
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I	Proteasome Complex Nucleus Cytoplasm Cytosol Proteasome Core Complex Proteasome Core Complex, Beta-subunit Complex Extracellular Exosome Spermatoproteasome Complex
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Endopeptidase Activity Threonine-type Endopeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Sensory Perception Of Sound Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Immune System Process Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process
Pathways		Respiratory electron transport Complex I biogenesis	ER-Phagosome pathway Cross-presentation of soluble exogenous antigens (endosomes) Proteasome assembly Proteasome assembly Antigen processing: Ub, ATP-independent proteasomal degradation
Drugs		NADH	Carfilzomib
Diseases
GWAS			Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 23266558) Disc degeneration (lumbar) ( 22993228) Hip circumference adjusted for BMI ( 34021172) IgA nephropathy ( 25305756) Nephropathy ( 21399633) Platelet distribution width ( 27863252) Rosacea symptom severity ( 29771307) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Systemic lupus erythematosus ( 32771030)
Interacting Genes		12 interacting genes: ELP1 FEZ1 GDF9 HAP1 IMMT MAGEA11 MEF2A MYCBP2 RBBP6 SH3GL3 UBC XRN1	8 interacting genes: CRYGA DDIT4L LAGE3 NCOA1 NCOA2 NCOA3 POMP PSMB10
Entrez ID		4715	5698
HPRD ID		03264	01514
Ensembl ID		ENSG00000147684	ENSG00000240065
Uniprot IDs		E9PH64 Q9Y6M9	A0A1U9X8D7 P28065
PDB IDs		5XTC 5XTD 5XTH 5XTI	6AVO 6E5B 7AWE 7B12 9FST
Enriched GO Terms of Interacting Partners?		Mitochondrion Localization Regulation Of Organelle Transport Along Microtubule Regulation Of Microtubule-based Movement Mitochondrion Distribution	Cellular Response To Thyroglobulin Triiodothyronine Nuclear Receptor Binding Response To Thyroglobulin Triiodothyronine Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Adipose Tissue Development Nuclear Receptor-mediated Signaling Pathway Regulation Of Adipose Tissue Development Protein-lysine-acetyltransferase Activity Protein Dimerization Activity Histone Acetyltransferase Activity Response To Progesterone Intracellular Receptor Signaling Pathway MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter By Galactose MRNA Transcription Transcription Coactivator Activity Histone H4K5ac Reader Activity Histone H4K12ac Reader Activity Acetylation-dependent Protein Binding Labyrinthine Layer Morphogenesis Regulation Of Cellular Response To Insulin Stimulus Cellular Response To Hormone Stimulus Neural Tube Closure Tube Closure Response To Lipid Positive Regulation Of Female Receptivity Response To Retinoic Acid Histone H3K14ac Reader Activity Response To Estradiol Vitamin D Receptor Signaling Pathway
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