MYO1A and NAB2

Data Source: HiPPIP (Novel)

		MYO1A	NAB2
Name		myosin IA	NGFI-A binding protein 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Filament Plasma Membrane Microvillus Brush Border Basal Plasma Membrane Actin Cytoskeleton Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Myosin Complex Cortical Actin Cytoskeleton Filamentous Actin Plasma Membrane Raft Plasma Membrane Bounded Cell Projection	Nucleus Nucleoplasm
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Calmodulin Binding ATP Binding Actin Filament Binding	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Endocytosis Actin Filament Organization Sensory Perception Of Sound Cell Projection Organization Microvillus Assembly Actin Filament-based Movement Vesicle Localization	Endochondral Ossification Regulation Of DNA-templated Transcription Schwann Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase III Myelination Regulation Of Epidermis Development Negative Regulation Of DNA-templated Transcription
Pathways		None	NGF-stimulated transcription NGF-stimulated transcription EGR2 and SOX10-mediated initiation of Schwann cell myelination
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011 ) Asthma ( 31619474 31959851 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Bipolar disorder ( 31043756 ) Heel bone mineral density ( 30598549 ) Red cell distribution width ( 32888494 ) Schizophrenia ( 25056061 )	Allergic disease (asthma, hay fever or eczema) ( 29785011 ) Asthma ( 29273806 31361310 31619474 31959851 ) Asthma (adult onset) ( 31036433 ) Asthma (childhood onset) ( 31036433 ) Asthma or allergic disease (pleiotropy) ( 29785011 ) Bipolar disorder ( 31043756 ) IgE levels ( 22075330 ) Schizophrenia ( 25056061 29483656 )
Novel Interactors		1 novel interactors: NAB2	7 novel interactors: APH1B HOXA10 HRH1 LRP1 MYO1A RDH5 SCN1A
Interacting Genes		2 interacting genes: ACTG1 CNN1	80 interacting genes: ANK3 ANKRD11 CBX8 CCDC187 CCDC33 CCDC57 CCHCR1 CDC23 CTAG1A CTAG1B CTNNA3 CWF19L2 DDX6 DGCR6 DGCR6L DRG2 EGR1 EGR2 ELOA ENKD1 EXOC8 FAM200C FAM9A GCC1 GOLGA6L9 HSF2BP JAKMIP2 KIF9 KIFC3 KRT34 KRT40 KRTAP10-3 KRTAP10-8 LENG1 LMNA LNX1 MAPK3 MCM7 MCRS1 MDFI MORF4L1 MORF4L2 NDOR1 NEDD9 NME7 NOTCH2NLA NTAQ1 PHF1 PHOSPHO2 PIK3R3 PIN1 PLOD3 PRKAA2 PRKAB2 PSMA1 QARS1 RBPMS RFC5 RINT1 SCNM1 SMARCD1 SORBS3 SPG21 SUMO1P1 TCEA2 TCEANC TCHP TGIF2LY TLE5 TRAF2 TRIM23 TSGA10 TSGA10IP TTC19 USP2 UTP14C ZMAT2 ZMYND12 ZMYND19 ZNF417
Entrez ID		4640	4665
HPRD ID		08371	03854
Ensembl ID		ENSG00000166866	ENSG00000166886
Uniprot IDs		B2R643 Q9UBC5	Q15742
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Basal Body Patch Actomyosin Structure Organization Protein Localization To Bicellular Tight Junction Structural Constituent Of Postsynaptic Actin Cytoskeleton Regulation Of Transepithelial Transport Actin Cytoskeleton Organization Actin Cytoskeleton Dense Body Morphogenesis Of A Polarized Epithelium Negative Regulation Of Transcription By RNA Polymerase III Schwann Cell Differentiation Actin Filament-based Process Profilin Binding Focal Adhesion Postsynaptic Actin Cytoskeleton Organization Protein Localization To Cell-cell Junction Calyx Of Held Postsynaptic Cytoskeleton Organization Filamentous Actin Apical Junction Complex NuA4 Histone Acetyltransferase Complex Regulation Of Synaptic Vesicle Endocytosis Regulation Of Synaptic Vesicle Recycling Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Endochondral Ossification Regulation Of Transcription By RNA Polymerase III Maintenance Of Blood-brain Barrier Sarcomere Organization	None