KPRP and RBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KPRP	RBP3
Description		keratinocyte proline rich protein	retinol binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Extracellular Exosome	Extracellular Region Extracellular Space Interphotoreceptor Matrix Cone Matrix Sheath Extracellular Vesicle
	Molecular Function	Protein Binding	Retinoid Binding Protein Binding Serine-type Peptidase Activity Retinal Binding Retinol Binding
	Biological Process	Desmosome Organization Inflammatory Response Epidermis Development Skin Development Establishment Of Skin Barrier	Retinoid Metabolic Process Proteolysis Lipid Metabolic Process Visual Perception
Pathways		Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin	The retinoid cycle in cones (daylight vision) The canonical retinoid cycle in rods (twilight vision)
Drugs			Lapachone
Diseases
GWAS		Asthma ( 31619474) Psoriasis ( 25854761)	Corneal curvature ( 24963161) Macular thickness ( 30535121)
Interacting Genes		110 interacting genes: ACTMAP AKAP8L ANKS1A ATG9A BTC CATSPER1 CCDC57 CES1 CKS1B CLCNKA CNFN CNNM3 COL8A1 CREB5 CYSRT1 DARS1-AS1 DMRT3 DYRK1A EIF3E ESR2 FAM221B FAM72B FBXO17 FCHO1 FHL2 FHL3 FRS3 GNE GRAP2 GRB2 GUCD1 HCK HEXIM2 HNRNPF HOXA1 HOXC8 HSD3B7 ITGB4 ITIH6 KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP12-3 KRTAP13-2 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP3-2 KRTAP4-2 KRTAP4-5 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-3 LCE3A LCE3C LCE3D LCE3E LIMS1 LMO2 LNX1 MAPKBP1 MEOX2 MGAT5B MIIP MLH1 NBPF19 NCK2 NID2 NOTCH2NLA NPBWR2 NR4A3 NTN4 NUFIP2 OTX1 PDGFRB PHLDA1 PLA2G10 PLSCR4 POU4F2 PPIL1 RANBP3 RBP3 RGL2 RNF38 SAXO4 SEMA3B SH3KBP1 SLC15A2 SPRED2 SPRY1 SPRY3 STK16 TEKT4 TFAP2D TNS2 TRIM42 TRIP6 UBASH3A UBASH3B VGLL3 VWC2 ZNF587	15 interacting genes: CDC23 CREB5 CYSRT1 EFEMP2 HOXA1 HR HSD3B7 KPRP KRTAP10-5 MGAT5B NID2 NOTCH1 PLSCR4 POU4F2 SPAG8
Entrez ID		448834	5949
HPRD ID		18838	01581
Ensembl ID		ENSG00000203786	ENSG00000265203
Uniprot IDs		Q5T749	P10745
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Protein Binding Keratin Filament Keratinization	Artery Development Semicircular Canal Formation Artery Morphogenesis Abducens Nerve Formation Optokinetic Behavior MAML1-RBP-Jkappa- ICN1 Complex Apoptotic Process Involved In Embryonic Digit Morphogenesis Vascular Associated Smooth Muscle Cell Development Regulation Of Extracellular Matrix Organization Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Vasculogenesis Involved In Coronary Vascular Morphogenesis Venous Endothelial Cell Differentiation Negative Regulation Of Inner Ear Auditory Receptor Cell Differentiation Distal Tubule Development Muscle Tissue Morphogenesis Regulation Of Smooth Muscle Cell Differentiation Epidermis Development Auditory Receptor Cell Fate Commitment Notch Signaling Involved In Heart Development Positive Regulation Of Muscle Cell Differentiation Regulation Of Aorta Morphogenesis Growth Involved In Heart Morphogenesis Negative Regulation Of Lymphoid Progenitor Cell Differentiation Negative Regulation Of Inner Ear Receptor Cell Differentiation Muscle Cell Development Chromatin DNA Binding Epidermal Cell Fate Specification Endocardium Morphogenesis Coronary Sinus Valve Morphogenesis Retinal Cone Cell Differentiation Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Pro-B Cell Differentiation Negative Regulation Of Neuron Differentiation Calcium Ion Binding Cardiac Right Ventricle Formation Glomerular Mesangial Cell Development Cell Migration Involved In Endocardial Cushion Formation Chemical Synaptic Transmission, Postsynaptic Foregut Morphogenesis Compartment Pattern Specification Mitral Valve Formation Arterial Endothelial Cell Differentiation Cellular Response To Tumor Cell Regulation Of Cell Adhesion Involved In Heart Morphogenesis Positive Regulation Of Smooth Muscle Cell Differentiation Tissue Development Cardiac Vascular Smooth Muscle Cell Development Negative Regulation Of Extracellular Matrix Constituent Secretion Epithelium Development Positive Regulation Of Aorta Morphogenesis
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