SMCO3 and TRIM39

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SMCO3	TRIM39
Gene Name		single-pass membrane protein with coiled-coil domains 3	tripartite motif containing 39
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Mitochondrion Cytosol
	Molecular Function		Protein Binding Zinc Ion Binding Ligase Activity Identical Protein Binding
	Biological Process		Apoptotic Process Protein Ubiquitination Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: MAPK9 TRIM39	52 interactors: APP CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 KDM1A LNX1 LXN MED18 MNAT1 OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMD9 RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1 UBTD2 UBXN1 UBXN6 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26
Entrez ID		440087	56658
HPRD ID		18442	09298
Ensembl ID		ENSG00000179256	ENSG00000204599
Uniprot IDs		A2RU48	Q9HCM9
PDB IDs			2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination JUN Phosphorylation Positive Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Positive Regulation Of Prostaglandin Secretion Positive Regulation Of Icosanoid Secretion Apoptotic Process Programmed Cell Death Positive Regulation Of Fatty Acid Transport Cell Death Death Positive Regulation Of Macrophage Derived Foam Cell Differentiation Release Of Cytochrome C From Mitochondria Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of Fatty Acid Transport Positive Regulation Of Signal Transduction Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Chemokine Production Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Apoptotic Process Response To Amine Regulation Of Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of Chemokine Production Cellular Response To Interleukin-1 Response To Cadmium Ion Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Lipid Transport Toll-like Receptor 2 Signaling Pathway Cellular Response To UV Positive Regulation Of Lipid Biosynthetic Process Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Reactive Oxygen Species Biosynthetic Process Protein Targeting To Mitochondrion MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Metabolic Process Regulation Of Proteolysis Regulation Of Protein Ubiquitination Protein K63-linked Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Cell Cycle Phase Transition Toll-like Receptor 4 Signaling Pathway Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Toll-like Receptor Signaling Pathway Regulation Of Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Cellular Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Cell Cycle Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Activation Of Innate Immune Response
Tagcloud ?			293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Difference) ?			293t aeromonas aggregate b30 bloodthirsty btr18 btr20 btr21 btr22 danio deduced e3 gill hydrophila intestine ligase mentioned multigene nj rbcc remarkably rerio tripartite ubch6 ubiquitin ubiquitylated ubiquitylation zebrafish
Tagcloud (Intersection) ?