MIR15A and TRMT10C

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR15A	TRMT10C
Description		microRNA 15a	tRNA methyltransferase 10C, mitochondrial RNase P subunit
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Mitochondrial Ribonuclease P Complex Mitochondrial Nucleoid TRNA Methyltransferase Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	TRNA Binding RNA Binding Protein Binding Methyltransferase Activity Transferase Activity Identical Protein Binding TRNA (guanosine(9)-N1)-methyltransferase Activity TRNA (adenine(9)-N1)-methyltransferase Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Angiogenesis MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Apoptotic Process Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Inflammatory Response Cellular Response To Glucose Stimulus Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Mitochondrial RNA 5'-end Processing MRNA Processing TRNA Processing Methylation Positive Regulation Of Mitochondrial Translation Mitochondrial TRNA Methylation Mitochondrial TRNA Processing Mitochondrial TRNA 5'-end Processing Mitochondrial TRNA 3'-end Processing
Pathways			tRNA processing in the mitochondrion tRNA modification in the mitochondrion rRNA processing in the mitochondrion
Drugs
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30643258) Allergic disease (asthma, hay fever or eczema) ( 29083406) Diastolic blood pressure ( 30224653) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes		73 interacting genes: AIMP1 AIMP2 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DDX49 DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUF60 QARS1 RARS1 RBM14 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 SYNCRIP TAF15 TRA2A TRA2B TRIM71 TRMT10C UPF1 UTP20 YBX1 YBX3 ZNF346	5 interacting genes: MIR15A MIRLET7A3 MT-TI OGT WEE2-AS1
Entrez ID		406948	54931
HPRD ID			15240
Ensembl ID		ENSG00000283785	ENSG00000174173
Uniprot IDs			Q7L0Y3
PDB IDs			5NFJ 7ONU 8CBK 8CBL 8CBM 8CBO 8RR1 8RR3 8RR4 9EY0 9EY1 9EY2 9GCH
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Binding Regulation Of RNA Splicing Ribonucleoprotein Complex Nucleoplasm Nucleus Spliceosomal Complex Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of Translation MiRNA Binding Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Processing Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression RNA Stabilization Regulation Of Macromolecule Biosynthetic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity MRNA 3'-UTR Binding TRNA Aminoacylation MRNA Stabilization Positive Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process TRNA Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation Ligase Activity Positive Regulation Of Macromolecule Biosynthetic Process Nucleolus Regulation Of Primary Metabolic Process Cytoplasmic Stress Granule Regulation Of Metabolic Process	Protein N-acetylglucosaminyltransferase Complex Cellular Response To Glucose Stimulus Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Carbohydrate Stimulus Intracellular Glucose Homeostasis RISC Complex Post-transcriptional Regulation Of Gene Expression MiRNA-mediated Post-transcriptional Gene Silencing Response To Monosaccharide Response To Glucose Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Response To Carbohydrate Protein O-acetylglucosaminyltransferase Activity Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Translation Pre-mRNA 5'-splice Site Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbohydrate Homeostasis Glucose Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription MRNA 5'-splice Site Recognition Regulation Of Transcription By Glucose Negative Regulation Of Gene Expression NSL Complex Negative Regulation Of Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Locomotion Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Translation U1 SnRNP Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Execution Phase Of Apoptosis
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?