IGF2BP1

Gene Name		insulin-like growth factor 2 mRNA binding protein 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Lamellipodium Filopodium Axon Growth Cone Ribonucleoprotein Complex Dendritic Spine Perinuclear Region Of Cytoplasm CRD-mediated MRNA Stability Complex
	Molecular Function	Nucleotide Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) RNA Binding Translation Regulator Activity MRNA 5'-UTR Binding
	Biological Process	Gene Expression Regulation Of MRNA Stability Involved In Response To Stress Negative Regulation Of Translation Regulation Of Cytokine Biosynthetic Process MRNA Transport CRD-mediated MRNA Stabilization
Pathways		Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Prostate cancer ( 23535732)
Protein-protein Interactions		1 interactors: CTNNB1
Entrez ID		10642
HPRD ID		09752
Ensembl ID		ENSG00000159217
Uniprot IDs		Q9NZI8
PDB IDs		3KRM
Enriched GO Terms of Interacting Partners?		Schwann Cell Proliferation Negative Regulation Of Mitotic Cell Cycle, Embryonic Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Positive Regulation Of Determination Of Dorsal Identity Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lung Induction Central Nervous System Vasculogenesis Trachea Formation Cellular Response To Indole-3-methanol Regulation Of Centromeric Sister Chromatid Cohesion Renal Vesicle Formation Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Protein Sumoylation Positive Regulation Of Branching Involved In Lung Morphogenesis Regulation Of Secondary Heart Field Cardioblast Proliferation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Branching Involved In Lung Morphogenesis Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Fungiform Papilla Formation Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Establishment Of Blood-brain Barrier Fungiform Papilla Morphogenesis Glial Cell Proliferation Metanephric Renal Vesicle Morphogenesis Endothelial Tube Morphogenesis Renal Vesicle Morphogenesis Sympathetic Ganglion Development Endodermal Cell Fate Commitment Fungiform Papilla Development Regulation Of Sister Chromatid Cohesion Neural Plate Development Positive Regulation Of Endothelial Cell Differentiation Mesenchymal Cell Proliferation Lung-associated Mesenchyme Development Mesenchymal To Epithelial Transition Epithelial Cell Differentiation Involved In Prostate Gland Development Trachea Morphogenesis Positive Regulation Of Glycoprotein Biosynthetic Process Genitalia Morphogenesis
Tagcloud ?		accordingly braf carcinogenesis certainly depends depletion hcc hence hepatocarcinogenesis hepatocellular messenger mki67 myc offer oncogene oncogenes options posttranscriptional protumorigenic pten rb rbp rbps representing revealing stabilizes stepwise suppressor xenograft