MIRLET7C and ZNF346

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIRLET7C	ZNF346
Description		microRNA let-7c	zinc finger protein 346
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm RISC Complex Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding Double-stranded RNA Binding Protein Binding Zinc Ion Binding Enzyme Binding MiRNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-8 Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Receptor Signaling Pathway Via STAT
Pathways
Drugs
Diseases
GWAS			Height ( 28552196 31562340) Type 2 diabetes ( 30718926) Uterine fibroids ( 30194396 31649266) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		96 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B ATXN2L C1QBP CHERP CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RBM4B RBMS2 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TENT2 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	67 interacting genes: ADARB1 ANKHD1 EIF2AK2 ILF3 LNX1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR141 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18B MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR214 MIR221 MIR222 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR98 MIRLET7A1 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7I NKRF RNF10 RNF8 STRBP TARBP2 XPO5
Entrez ID		406885	23567
HPRD ID			05606
Ensembl ID		ENSG00000199030	ENSG00000113761
Uniprot IDs			B7Z4J8 B7Z4N4 D6RJ07 Q9UL40
PDB IDs			2MKD 2MKN
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Metabolic Process Nucleic Acid Metabolic Process MRNA Processing RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Splicing Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Nucleus Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleoplasm MiRNA Binding Spliceosomal Complex Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of RNA Stability Negative Regulation Of MRNA Catabolic Process RNA Stabilization TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Stability TRNA Aminoacylation MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Nucleolus Positive Regulation Of Cytoplasmic Translation Negative Regulation Of Translation TRNA Metabolic Process RNA 3'-end Processing Paraspeckles	MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cytokine Production Negative Regulation Of Cell Migration Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of MRNA Stability Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of RNA Stability Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Endothelial Cell Migration Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Signal Transduction Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Cell Migration Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Cytokine Production
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?