MIRLET7A1 and YBX3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIRLET7A1	YBX3
Description		microRNA let-7a-1	Y-box binding protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex Extracellular Exosome Extracellular Vesicle	Nucleus Cytoplasm Cytosol Bicellular Tight Junction Synapse Perinuclear Region Of Cytoplasm
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Small GTPase Binding Ribonucleoprotein Complex Binding
	Biological Process	Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Apoptotic Process Spermatogenesis Male Gonad Development Fertilization Regulation Of Gene Expression Ectopic Germ Cell Programmed Cell Death Negative Regulation Of Apoptotic Process Positive Regulation Of Organ Growth Negative Regulation Of Skeletal Muscle Tissue Development Negative Regulation Of Developmental Process Negative Regulation Of Necroptotic Process 3'-UTR-mediated MRNA Stabilization Cellular Response To Tumor Necrosis Factor Cellular Hyperosmotic Response Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Negative Regulation Of Reproductive Process Positive Regulation Of Cytoplasmic Translation
Pathways
Drugs
Diseases
GWAS			Coronary artery disease ( 33020668) Refractive error ( 32231278)
Interacting Genes		101 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF2 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RTCB SAFB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	90 interacting genes: CDK4 CDK5 DANCR GSK3B IL7R LINC00624 MAILR MAPK1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NEIL3 NFYB OGT PCBP2 RALA SLC26A4-AS1 SRPK2 SYMPK TJP1 VEGFA
Entrez ID		406881	8531
HPRD ID			10347
Ensembl ID		ENSG00000199165	ENSG00000060138
Uniprot IDs			P16989
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Processing Nucleobase-containing Compound Metabolic Process RNA Splicing MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression Nucleus MiRNA Binding Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleoplasm Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Cytoplasmic Stress Granule Spliceosomal Complex Catalytic Step 2 Spliceosome Regulation Of Translation Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Stability Negative Regulation Of RNA Catabolic Process Regulation Of MRNA Stability MRNA 3'-UTR Binding Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA 3'-end Processing Regulation Of Macromolecule Metabolic Process MRNA Stabilization MiRNA Processing Regulation Of Primary Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Histone MRNA Metabolic Process Negative Regulation Of Translation Regulation Of Metabolic Process TRNA Metabolic Process TRNA Aminoacylation Nucleolus Positive Regulation Of Gene Expression	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Regulation Of Angiogenesis Negative Regulation Of Locomotion Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Negative Regulation Of Cytokine Production Negative Regulation Of Vasculature Development Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Translation Negative Regulation Of Developmental Process Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Locomotion Regulation Of MRNA Stability Negative Regulation Of Protein Metabolic Process Regulation Of RNA Stability Regulation Of Endothelial Cell Migration Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Space Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
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