ARHGAP5 and RND2

Number of citations of the paper that reports this interaction (PMID 12842009)
43

Data Source:
BioGRID (pull down)

		ARHGAP5	RND2
Gene Name		Rho GTPase activating protein 5	Rho family GTPase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Acrosomal Membrane Early Endosome
	Molecular Function	GTPase Activity Rho GTPase Activator Activity Protein Binding GTP Binding SH2 Domain Binding	GTPase Activity Protein Binding GTP Binding Protein N-terminus Binding
	Biological Process	Positive Regulation Of Mesenchymal Cell Proliferation Cell Adhesion Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Metabolic Process Regulation Of Cell Size Positive Regulation Of Cell Migration Mammary Gland Development Positive Regulation Of Rho GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Signal Transduction Small GTPase Mediated Signal Transduction Metabolic Process Positive Regulation Of Collateral Sprouting
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ADRB2 ITGA5 ITGB1 PTK2B PTPN18 RASA1 RHOA RND1 RND2 RND3 SMURF2	6 interactors: ARHGAP5 FNBP1 MEOX2 RACGAP1 UBXN11 VPS4A
Entrez ID		394	8153
HPRD ID		04060	03332
Ensembl ID		ENSG00000100852	ENSG00000108830
Uniprot IDs		Q13017	P52198
PDB IDs		2EE4 2EE5
Enriched GO Terms of Interacting Partners?		Axon Guidance Neuron Projection Development Regulation Of Cell-substrate Adhesion Cell Junction Assembly Generation Of Neurons Neuron Development Neurogenesis Axonogenesis Positive Regulation Of Neuron Projection Development Signal Transduction Axon Development Cell Morphogenesis Involved In Neuron Differentiation Response To External Stimulus Actin Cytoskeleton Organization Neuron Differentiation Chemotaxis Cell-cell Adhesion Mediated By Integrin Regulation Of Cell Adhesion Cell Projection Organization Signaling Positive Regulation Of Cell Projection Organization Neuron Projection Morphogenesis Actin Filament-based Process Cell Communication Locomotion Positive Regulation Of Signal Transduction Cell Morphogenesis Involved In Differentiation Positive Regulation Of Neuron Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Adhesion Mediated By Integrin Positive Regulation Of Cell-substrate Adhesion Nervous System Development Integrin-mediated Signaling Pathway Regulation Of Neuron Projection Development Cell Differentiation Movement Of Cell Or Subcellular Component Negative Regulation Of Anoikis Cell Projection Morphogenesis Cellular Response To Stimulus Cell Part Morphogenesis Positive Regulation Of Neurogenesis Blood Vessel Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Anoikis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cell Morphogenesis Blood Vessel Endothelial Cell Migration Heterotypic Cell-cell Adhesion Regulation Of Cell Projection Organization Positive Regulation Of Cell Development	Cell Separation After Cytokinesis Regulation Of Cytokinesis Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Abscission Somite Specification Mitotic Spindle Midzone Assembly Viral Budding Via Host ESCRT Complex Regulation Of Cell Division Mitotic Spindle Elongation Mitotic Cytokinetic Process Viral Budding Negative Regulation Of Cytokinesis Spindle Midzone Assembly Mitotic Nuclear Division Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Segment Specification Cell Division Mitotic Spindle Assembly Regulation Of Attachment Of Spindle Microtubules To Kinetochore Virion Assembly Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Metaphase Plate Congression
Tagcloud ?		10a 200c 30a 30c cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3	actin actomyosin antagonise atypical bypass contractility cytoskeleton explain extension gtp gtpase hydrolyse inhibiting limit neurite propose reducing regulating regulators relatives rho rhoa rhoe rnd1 rnd3 rock separate smooth thereby
Tagcloud (Difference) ?		10a 200c 30a 30c cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs nrp2 oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3	actin actomyosin antagonise atypical bypass contractility cytoskeleton explain extension gtp gtpase hydrolyse inhibiting limit neurite propose reducing regulating regulators relatives rho rhoa rhoe rnd1 rnd3 rock separate smooth thereby
Tagcloud (Intersection) ?