ZDHHC1 and KRT83

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZDHHC1	KRT83
Description		zDHHC palmitoyltransferase 1	keratin 83
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Endosome Membrane Membrane Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament
	Molecular Function	DNA Binding Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Membrane NLRP3 Inflammasome Complex Assembly Antiviral Innate Immune Response Positive Regulation Of NLRP3 Inflammasome Complex Assembly	Epidermis Development Keratinization Hair Cycle Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS		Body size at age 10 ( 32376654) Bone mineral density ( 31790847) Empathy quotient ( 29527006) Refractive error ( 32231278) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		18 interacting genes: CYSRT1 GOPC KRT31 KRT34 KRT83 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP9-2 KRTAP9-3 MDFI NBPF19 NOTCH2NLA	42 interacting genes: ADAM12 ANKS1A C11orf87 CEP57 CREB5 CYSRT1 DSCAM GEM GNE GSTP1 HOXA1 KRT15 KRT16 KRT19 KRT25 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-3 KRTAP3-3 KRTAP6-2 MEOX2 NBPF19 NOTCH2NLA NRF1 OIP5 PITX1 PLEKHN1 POU4F2 ZDHHC1
Entrez ID		29800	3889
HPRD ID		15707	09097
Ensembl ID		ENSG00000159714	ENSG00000170523
Uniprot IDs		I3L202 Q8WTX9	P78385
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Epidermis Development Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Cytosol Negative Regulation Of Anion Channel Activity Identical Protein Binding	Keratin Filament Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cellular Developmental Process Cytosol Hair Cycle Extracellular Exosome Cell Differentiation Epidermis Development Developmental Process Structural Constituent Of Cytoskeleton Tissue Development Organelle Organization
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