CFAP141 and PTGES2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CFAP141	PTGES2
Description		cilia and flagella associated protein 141	prostaglandin E synthase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Microtubule Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath	Golgi Membrane Extracellular Region Nucleus Cytoplasm Mitochondrion Golgi Apparatus Cytosol Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	DNA Binding Protein Binding Lyase Activity Isomerase Activity Heme Binding 12-hydroxyheptadecatrienoic Acid Synthase Activity Glutathione Binding Prostaglandin-E Synthase Activity
	Biological Process	Flagellated Sperm Motility	Prostaglandin Biosynthetic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Prostaglandin Metabolic Process Positive Regulation Of DNA-templated Transcription Prostanoid Biosynthetic Process Secretion
Pathways			Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Neutrophil degranulation
Drugs
Diseases			Penile cancer
GWAS			Body mass index ( 26426971)
Interacting Genes		1 interacting genes: PTGES2	6 interacting genes: ADRB2 CEBPB CFAP141 EXOSC10 HSPA13 PTGFR
Entrez ID		388701	80142
HPRD ID		17373	07458
Ensembl ID		ENSG00000163263	ENSG00000148334
Uniprot IDs		Q5VU69	A0A7I2V5X6 A6NHH0 B3KPZ2 B4DWP1 Q9H7Z7
PDB IDs		7UNG 8J07
Enriched GO Terms of Interacting Partners?		12-hydroxyheptadecatrienoic Acid Synthase Activity Prostaglandin-E Synthase Activity Glutathione Binding Prostaglandin Biosynthetic Process Prostanoid Biosynthetic Process Prostanoid Metabolic Process Prostaglandin Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Icosanoid Biosynthetic Process Azurophil Granule Lumen Unsaturated Fatty Acid Metabolic Process Icosanoid Metabolic Process Fatty Acid Biosynthetic Process Heme Binding Lyase Activity Isomerase Activity	Regulation Of Sodium-dependent Phosphate Transport Regulation Of Phosphate Transport Brown Fat Cell Differentiation Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Mini Excitatory Postsynaptic Potential Photoreactive Repair Nuclear Polyadenylation-dependent Antisense Transcript Catabolic Process Prostaglandin F Receptor Activity Beta2-adrenergic Receptor Activity Granuloma Formation C/EBP Complex Blue Light Signaling Pathway DNA (6-4) Photolyase Activity Deoxyribodipyrimidine Photo-lyase Activity Blue Light Photoreceptor Activity Nuclear Polyadenylation-dependent SnoRNA Catabolic Process Nuclear Polyadenylation-dependent SnRNA Catabolic Process Nuclear Polyadenylation-dependent CUT Catabolic Process Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Positive Regulation Of Cold-induced Thermogenesis T-helper 1 Cell Activation Kinase Binding CHOP-C/EBP Complex Positive Regulation Of Sodium-dependent Phosphate Transport Cry-Per Complex Regulation Of Homologous Chromosome Segregation U5 SnRNA Binding Norepinephrine Binding Negative Regulation Of Glucocorticoid Secretion Sno(s)RNA Catabolic Process Positive Regulation Of MRNA Cis Splicing, Via Spliceosome Response To Psychosocial Stress Fat Cell Differentiation Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway SnRNA Catabolic Process CUT Catabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Autophagosome Maturation Regulation Of Cold-induced Thermogenesis Heat Generation Nucleic Acid Metabolic Process Hepatocyte Proliferation Negative Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Response To Blue Light Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRNA Surveillance TRAMP-dependent TRNA Surveillance Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?