LINC02875 and SH2D2A

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		LINC02875	SH2D2A
Description		long intergenic non-protein coding RNA 2875	SH2 domain containing 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding SH3 Domain Binding
	Biological Process		Angiogenesis Signal Transduction Cell Differentiation T Cell Proliferation
Pathways			VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS			Autoimmune thyroid disease ( 32581359) Platelet count ( 27863252 32888494) Plateletcrit ( 32888494) Sjögren's syndrome ( 28076899)
Interacting Genes		7 interacting genes: APPL2 DAPK1 KDM1A PRMT6 SH2D2A SUV39H1 TRAF2	34 interacting genes: APPL1 AR ARID5A CRK DAPK1 EGFR ERBB2 ERBB3 ERBB4 GAB1 ITK KDR KIT LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MET MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1
Entrez ID		388407	9047
HPRD ID		14202	05152
Ensembl ID		ENSG00000187013	ENSG00000027869
Uniprot IDs			Q5UBZ2 Q5UBZ3 Q9NP31
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Histone Methyltransferase Activity Histone H3 Methyltransferase Activity Negative Regulation Of Macromolecule Biosynthetic Process DAPK1-calmodulin Complex Negative Regulation Of Biosynthetic Process Positive Regulation Of Autophagic Cell Death Chromatin Binding TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Regulation Of Neural Precursor Cell Proliferation Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Positive Regulation Of Cold-induced Thermogenesis Histone H3R2 Methyltransferase Activity Histone H2AR3 Methyltransferase Activity Positive Regulation Of Macropinocytosis Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis ENoSc Complex Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone Arginine N-methyltransferase Activity Early Phagosome Membrane Cold Acclimation Regulation Of NMDA Receptor Activity Cellular Response To Stress Regulation Of Protein Metabolic Process Histone H3K9 Trimethyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process Chromatin Remodeling Regulation Of Multicellular Organismal Development Methyltransferase Activity RDNA Heterochromatin Sphingolipid Binding IRE1-TRAF2-ASK1 Complex CD27 Signaling Pathway Tumor Necrosis Factor Receptor Superfamily Complex MRF Binding Protein Demethylase Activity Regulation Of Cold-induced Thermogenesis Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Macropinosome Regulation Of Gene Expression Regulation Of Signal Transduction Regulation Of Macromolecule Biosynthetic Process	Protein Tyrosine Kinase Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Kinase Activity Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity Positive Regulation Of Signal Transduction ATP Binding Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Positive Regulation Of Epithelial Cell Proliferation Nucleotide Binding Signal Transduction Regulation Of Intracellular Signal Transduction ERBB Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell Communication Regulation Of MAPK Cascade Regulation Of Signaling Phosphorylation Peptidyl-tyrosine Phosphorylation Regulation Of Programmed Cell Death Transferase Activity Cellular Response To Growth Factor Stimulus Cellular Developmental Process Negative Regulation Of Programmed Cell Death Receptor Complex Cell Differentiation ERBB2 Signaling Pathway Protein Autophosphorylation Response To Growth Factor Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Basal Plasma Membrane Protein Phosphorylation Regulation Of Epithelial Cell Proliferation Protein Phosphatase Binding Negative Regulation Of Defense Response SH2 Domain Binding Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Non-membrane Spanning Protein Tyrosine Kinase Activity Negative Regulation Of Inflammatory Response Growth Factor Binding Positive Regulation Of Multicellular Organismal Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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