SLC16A12 and FXYD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC16A12	FXYD3
Description		solute carrier family 16 member 12	FXYD domain containing ion transport regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Creatine Transmembrane Transporter Activity Protein Binding Uniporter Activity Transmembrane Transporter Activity	Chloride Channel Activity Protein Binding Sodium Channel Regulator Activity ATPase Binding Ion Channel Regulator Activity
	Biological Process	Creatine Transmembrane Transport Creatinine Metabolic Process Transmembrane Transport Transport Across Blood-brain Barrier	Monoatomic Ion Transport Potassium Ion Transport Sodium Ion Transport Chloride Transport Regulation Of Monoatomic Ion Transport Chloride Transmembrane Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane
Pathways			Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		4 interacting genes: AQP6 CD79A FXYD3 GJA8	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35H1 SLC39A2 SLC61A1 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		387700	5349
HPRD ID		17365	05410
Ensembl ID		ENSG00000152779	ENSG00000089356
Uniprot IDs		Q6ZSM3	A0A1S5UZ23 Q14802 S4R445
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Chloride Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport Chloride Transport IgM B Cell Receptor Complex Carbon Dioxide Transmembrane Transporter Activity Transmembrane Transport Carbon Dioxide Transmembrane Transport B Cell Receptor Complex Gap Junction-mediated Intercellular Transport Monoatomic Anion Channel Activity Renal Water Transport Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity Ammonium Channel Activity Ammonium Transmembrane Transport Intercellular Transport Water Channel Activity Carbon Dioxide Transport Positive Regulation Of Sodium Ion Transmembrane Transport Connexin Complex Gap Junction Channel Activity One-carbon Compound Transport Water Transport Gap Junction Positive Regulation Of Sodium Ion Transport Sodium Channel Regulator Activity Fluid Transport Inorganic Ion Transmembrane Transport Channel Activity B Cell Proliferation Regulation Of Sodium Ion Transmembrane Transport Lens Development In Camera-type Eye Monoatomic Ion Transmembrane Transport Multivesicular Body B Cell Receptor Signaling Pathway Monoatomic Ion Transport Chloride Channel Activity Regulation Of Sodium Ion Transport	Membrane Transmembrane Transport Endoplasmic Reticulum Membrane Organic Anion Transport Endoplasmic Reticulum Protein Binding Pyrimidine Nucleotide-sugar Transmembrane Transport Nucleotide-sugar Transmembrane Transport Sterol Biosynthetic Process Monoatomic Ion Transport UDP-glucose Transmembrane Transport Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoatomic Cation Transport Plasma Membrane Zinc Ion Transmembrane Transport Zinc Ion Transport Bile Acid:sodium Symporter Activity Inorganic Ion Transmembrane Transport Organic Hydroxy Compound Transport Steroid Biosynthetic Process Cholesterol Biosynthetic Process Metal Ion Transport Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoatomic Anion Channel Activity Monoatomic Ion Transmembrane Transport Channel Activity Inorganic Cation Transmembrane Transport Nuclear Membrane Monoatomic Cation Transmembrane Transport Antiporter Activity Amine Transport Negative Regulation Of Response To Endoplasmic Reticulum Stress
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