KIF2A and CLSTN1

Number of citations: 32 (PubMedID 17332754)
Data Source: HPRD (in vivo)

		KIF2A	CLSTN1
Name		kinesin family member 2A	calsyntenin 1
Structure			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Ciliary Basal Body Mitotic Spindle Centriolar Subdistal Appendage	Golgi Membrane Extracellular Region Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Cell Surface Postsynaptic Density Membrane Cell Projection Neuron Projection Synapse Postsynaptic Membrane Postsynaptic Endosome Glutamatergic Synapse
	Molecular Function	Nucleotide Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity	Amyloid-beta Binding Calcium Ion Binding Protein Binding Kinesin Binding X11-like Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Microtubule Cytoskeleton Organization Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly	Regulation Of Cell Growth Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Positive Regulation Of Synaptic Transmission Positive Regulation Of Synapse Assembly Regulation Of Synapse Maturation Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	None
GWAS		Diastolic blood pressure ( 30224653 ) Heel bone mineral density x serum urate levels interaction ( 34046847 ) Mean corpuscular volume ( 32888494 ) Mean reticulocyte volume ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Metabolite levels ( 23823483 )	No GWAS studies recorded
Interacting Genes		14 interacting genes: CASK CEBPA CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B LMO2 LMO3 MRPL53 SUMO2	14 interacting genes: APBA2 APBB1 BAHCC1 COL17A1 KIF2A KLC1 KLC2 MCM3AP MDM2 PRNP SETDB1 SLK TOPBP1 TRIP12
Entrez ID		3796	22883
HPRD ID		03996	10837
Ensembl ID		ENSG00000068796	ENSG00000171603
Uniprot IDs		A0A6Q8PFA6 B0AZS5 O00139	B4E3Q1 O94985
PDB IDs		2GRY 6BBN	Not available
GO Terms Enriched among Interactors		Kinesin Binding	Kinesin Complex Amyloid-beta Binding Heterochromatin Organization Negative Regulation Of Protein Processing Negative Regulation Of Protein Maturation Chromatin Organization Chromatin Binding Cytoskeletal Motor Activity Kinesin Binding Response To Formaldehyde Cellular Response To Vitamin B1 Type 8 Metabotropic Glutamate Receptor Binding Kinesin I Complex Regulation Of Protein Processing Protein Destabilization Regulation Of Protein Maturation