RAB15 and RPH3A

Number of citations of the paper that reports this interaction (PMID 12578829)
33

Data Source:
HPRD (in vitro)

		RAB15	RPH3A
Gene Name		RAB15, member RAS oncogene family	rabphilin 3A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Endosome Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Primary Cilium	Golgi Apparatus Cytosol Synaptic Vesicle Extrinsic Component Of Membrane Cell Junction Secretory Granule Synaptic Vesicle Membrane Neuron Projection Protein Complex Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Zinc Ion Binding Selenium Binding Rab GTPase Binding Protein Complex Binding Phosphate Ion Binding Inositol 1,4,5 Trisphosphate Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Rab Protein Signal Transduction Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway	Intracellular Protein Transport
Pathways
Drugs
Diseases
GWAS			Platelet counts ( 22139419)
Protein-Protein Interactions		2 interactors: RABIF RPH3A	10 interactors: ADD2 CASK GCH1 NRXN1 RAB15 RAB27A RAB3A RAB3B RAB8A YWHAH
Entrez ID		376267	22895
HPRD ID		11467	15273
Ensembl ID		ENSG00000139998	ENSG00000089169
Uniprot IDs		G5EMR7 G5EMR8 P59190	Q9Y2J0
PDB IDs
Enriched GO Terms of Interacting Partners?			Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Protein Secretion Secretion Regulation Of Exocytosis Vesicle Localization Ras Protein Signal Transduction Secretion By Cell Regulation Of Cellular Localization Positive Regulation Of Regulated Secretory Pathway Regulation Of Secretion Neurotransmitter Secretion Regulation Of Synaptic Transmission Synaptic Vesicle Transport Exocytosis Positive Regulation Of Transport Cellular Protein Localization Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Establishment Of Protein Localization Organelle Localization Neurotransmitter Transport Regulation Of Regulated Secretory Pathway Intracellular Protein Transport Establishment Of Vesicle Localization Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Synaptic Transmission Protein Localization Small GTPase Mediated Signal Transduction Establishment Of Localization In Cell Establishment Of Organelle Localization Protein Transport Cellular Localization Intracellular Transport Cell-cell Signaling Intracellular Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Ion Transport Transport Vesicle-mediated Transport Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Secretion Membrane Organization Protein Localization To Membrane Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of Constitutive Secretory Pathway Protein Complex Assembly Involved In Synapse Maturation
Tagcloud ?			abeta25 cholinergic deafferentation downregulated dysfunction exocytosis immunoreactivity interacts involve neocortex neuritic neurofibrillary neuron neurotransmitter plaques postmortem postsynaptic presynaptic rab3a rabphilin reductions selectively snare synaptic synaptopathology tangles triggered vesicle
Tagcloud (Difference) ?			abeta25 cholinergic deafferentation downregulated dysfunction exocytosis immunoreactivity interacts involve neocortex neuritic neurofibrillary neuron neurotransmitter plaques postmortem postsynaptic presynaptic rab3a rabphilin reductions selectively snare synaptic synaptopathology tangles triggered vesicle
Tagcloud (Intersection) ?